B7MHP4 (SSUD_ECO45) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Alkanesulfonate monooxygenase
EC=1.14.14.5

Alternative name(s):
FMNH2-dependent aliphatic sulfonate monooxygenase

Gene names

Name:	ssuD
Ordered Locus Names:	ECS88_0963

Organism

Escherichia coli O45:K1 (strain S88 / ExPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

585035 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	381 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the desulfonation of aliphatic sulfonates By similarity. HAMAP MF_01229
Catalytic activity	An alkanesufonate (R-CH(2)-SO3H) + FMNH2 + O2 = an aldehyde (R-CHO) + FMN + sulfite + H2O. HAMAP MF_01229
Subunit structure	Homotetramer By similarity. HAMAP MF_01229
Miscellaneous	FMNH2 which is absolutely required for this enzymatic reaction, is provided by SsuE By similarity. HAMAP MF_01229
Sequence similarities	Belongs to the SsuD family.

Ontologies

Keywords
Ligand	FMN
Molecular function	Monooxygenase Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	alkanesulfonate monooxygenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 381	381	Alkanesulfonate monooxygenase HAMAP MF_01229		PRO_1000139616

Sequences

	Sequence		Length	Mass (Da)
	B7MHP4 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 3E720AC96D684B06	FASTA	381	41,672
	10 20 30 40 50 60 MSLNMFWFLP THGDGHYLGT EEGSRPVDHG YLQQIAQAAD RLGYTGVLIP TGRSCEDAWL 70 80 90 100 110 120 VAASMIPVTQ RLKFLVALRP SVTSPTVAAR QAATLDRLSN GRALFNLVTG SDPQELAGDG 130 140 150 160 170 180 VFLDHSERYE ASAEFTQVWR RLLLGETVDF NGKHIHVRGA KLLFPPIQQP YPPLYFGGSS 190 200 210 220 230 240 DVAQELAAEQ VDLYLTWGEP PELVKEKIEH VRAKAAAHGR KIRFGVRLHV IVRETNDEAW 250 260 270 280 290 300 QAAERLISRL DDETIAKAQA AFARTDSVGQ QRMAALHNGK RDNLEISPNL WAGVGLVRGG 310 320 330 340 350 360 AGTALVGDGP TVAARINEYA ALGIDSFVLS GYPHLEEAYR VGELLFPHLD VAIPEIPQPQ 370 380 PLNPQGEAVA NDFIPRNVAQ S

References

[1]

"Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths." Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P., Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H., Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E. , Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C., Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S., Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J., Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E. PLoS Genet. 5:E1000344-E1000344(2009) [PubMed: 19165319] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S88 / ExPEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU928161 Genomic DNA. Translation: CAR02295.1.
RefSeq	YP_002390753.1. NC_011742.1.
3D structure databases
ProteinModelPortal	B7MHP4.
SMR	B7MHP4. Positions 1-362.
ModBase	Search...
Protein-protein interaction databases
STRING	B7MHP4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000136259; EBESCP00000129743; EBESCG00000136415.
GeneID	7129678.
GenomeReviews	Gene locus ECS88_0963 in contig CU928161_GR.
PATRIC	18409647. VBIEscCol91599_0965.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000008394.
HOGENOM	HBG639644.
OMA	SLEGKHI.
ProtClustDB	PRK00719.
Enzyme and pathway databases
BioCyc	ECOL585035:ECS88_0963-MONOMER.
Family and domain databases
HAMAP	MF_01229. Alkanesulf_monooxygen. [Tree]
InterPro	IPR019911. Alkanesulphonate_mOase_FMN-dep. IPR011251. Luciferase-like_dom. [Graphical view]
Gene3D	G3DSA:3.20.20.30. Luciferase_like. 2 hits.
Pfam	PF00296. Bac_luciferase. 1 hit. [Graphical view]
SUPFAM	SSF51679. Luciferase_like. 1 hit.
TIGRFAMs	TIGR03565. Alk_sulf_monoox. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SSUD_ECO45

Accession

Primary (citable) accession number: B7MHP4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 10, 2009
Last modified:	January 25, 2012
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program