B7MHF6 (RIMK_ECO45) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal protein S6 modification protein

Gene names

Name:	rimK
Ordered Locus Names:	ECS88_0869

Organism

Escherichia coli O45:K1 (strain S88 / ExPEC) [Complete proteome] [HAMAP]

Taxonomic identifier

585035 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	300 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 By similarity. HAMAP-Rule MF_01552
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity.
Sequence similarities	Belongs to the RimK family. Contains 1 ATP-grasp domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	ATP-binding Magnesium Manganese Metal-binding Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cellular protein modification process Inferred from electronic annotation. Source: InterPro translation Inferred from electronic annotation. Source: HAMAP
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP catalytic activity Inferred from electronic annotation. Source: InterPro magnesium ion binding Inferred from electronic annotation. Source: HAMAP manganese ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 300	300	Ribosomal protein S6 modification protein HAMAP-Rule MF_01552		PRO_1000194367
Regions
	Domain	104 – 287	184	ATP-grasp
	Nucleotide binding	177 – 187	11	ATP By similarity
Sites
	Metal binding	248	1	Magnesium or manganese 1 By similarity
	Metal binding	260	1	Magnesium or manganese 1 By similarity
	Metal binding	260	1	Magnesium or manganese 2 By similarity
	Metal binding	262	1	Magnesium or manganese 2 By similarity
	Binding site	141	1	ATP By similarity
	Binding site	203	1	ATP By similarity

Sequences

	Sequence		Length	Mass (Da)
	B7MHF6 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: C0AF021292ED41DD	FASTA	300	32,436
	10 20 30 40 50 60 MKIAILSRDG TLYSCKRLRE AAIQRGHLVE ILDPLSCYMN INPAASSIHY KGRKLPHFDA 70 80 90 100 110 120 VIPRIGTAIT FYGTAALRQF EMLGSYPLNE SVAIARARDK LRSMQLLARQ GIDLPVTGIA 130 140 150 160 170 180 HSPDDTSDLI DMVGGAPLVV KLVEGTQGIG VVLAETRQAA ESVIDAFRGL NAHILVQEYI 190 200 210 220 230 240 KEAQGCDIRC LVVGDEVVAA IERRAKEGDF RSNLHRGGAA SVASITPQER EIAIKAARTM 250 260 270 280 290 300 ALDVAGVDIL RANRGPLVME VNASPGLEGI EKTTGIDIAG KMIRWIERHA TTEYCLKTGG

References

[1]

"Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths." Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P., Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H., Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E. , Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C., Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S., Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J., Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E. PLoS Genet. 5:E1000344-E1000344(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: S88 / ExPEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU928161 Genomic DNA. Translation: CAR02207.1.
RefSeq	YP_002390669.1. NC_011742.1.
3D structure databases
ProteinModelPortal	B7MHF6.
SMR	B7MHF6. Positions 73-285.
ModBase	Search...
Protein-protein interaction databases
STRING	585035.ECS88_0869.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAR02207; CAR02207; ECS88_0869.
GeneID	7129705.
KEGG	ecz:ECS88_0869.
PATRIC	18409459. VBIEscCol91599_0872.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0189.
HOGENOM	HOG000293092.
KO	K05844.
OMA	CREPRLY.
ProtClustDB	PRK10446.
Enzyme and pathway databases
BioCyc	ECOL585035:GJWP-875-MONOMER.
Family and domain databases
Gene3D	3.30.1490.20. 1 hit. 3.30.470.20. 1 hit. 3.40.50.20. 1 hit.
HAMAP	MF_01552. RimK.
InterPro	IPR011761. ATP-grasp. IPR013651. ATP-grasp_RimK-type. IPR013815. ATP_grasp_subdomain_1. IPR013816. ATP_grasp_subdomain_2. IPR016185. PreATP-grasp_dom. IPR023533. Ribosomal_S6_modifier_RimK. IPR004666. RpS6_RimK/Lys_biosynth_LsyX. [Graphical view]
Pfam	PF08443. RimK. 1 hit. [Graphical view]
TIGRFAMs	TIGR00768. rimK_fam. 1 hit.
PROSITE	PS50975. ATP_GRASP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

RIMK_ECO45

Accession

Primary (citable) accession number: B7MHF6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	March 24, 2009
Last modified:	May 1, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program