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B7MGM4

- 6PGL_ECO45

UniProt

B7MGM4 - 6PGL_ECO45

Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Escherichia coli O45:K1 (strain S88 / ExPEC)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (10 Feb 2009)
      Previous versions | rss
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    Functioni

    Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.UniRule annotation

    Catalytic activityi

    6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. 6-phosphogluconolactonase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. pentose-phosphate shunt Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Glucose metabolism

    Enzyme and pathway databases

    BioCyciECOL585035:GJWP-788-MONOMER.
    UniPathwayiUPA00115; UER00409.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    6-phosphogluconolactonaseUniRule annotation (EC:3.1.1.31UniRule annotation)
    Short name:
    6-P-gluconolactonaseUniRule annotation
    Gene namesi
    Name:pglUniRule annotation
    Ordered Locus Names:ECS88_0783
    OrganismiEscherichia coli O45:K1 (strain S88 / ExPEC)
    Taxonomic identifieri585035 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000747: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 3313316-phosphogluconolactonasePRO_1000148150Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei287 – 2871N6-acetyllysineUniRule annotation

    Keywords - PTMi

    Acetylation

    Interactioni

    Protein-protein interaction databases

    STRINGi585035.ECS88_0783.

    Structurei

    3D structure databases

    ProteinModelPortaliB7MGM4.
    SMRiB7MGM4. Positions 1-331.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cycloisomerase 2 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG2706.
    HOGENOMiHOG000257418.
    KOiK07404.
    OMAiDKRFLYV.
    OrthoDBiEOG615VK7.

    Family and domain databases

    Gene3Di2.130.10.10. 1 hit.
    HAMAPiMF_01605. 6P_gluconolactonase.
    InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
    IPR019405. Lactonase_7-beta_prop.
    IPR011045. N2O_reductase_N.
    IPR015943. WD40/YVTN_repeat-like_dom.
    [Graphical view]
    PfamiPF10282. Lactonase. 1 hit.
    [Graphical view]
    SUPFAMiSSF50974. SSF50974. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B7MGM4-1 [UniParc]FASTAAdd to Basket

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    MKQTVYIASP ESQQIHVWNL NHEGALTLTQ VVDVPGQVQP MVVSPDKRYL    50
    YVGVRPEFRV LAYRIAPDDG ALTFAAESAL PGSPTHISTD HLGQFVFVGS 100
    YNAGNVSVTR LEDGLPVGVV DVVEGLDGCH SANISPDNRT LWVPALKQDR 150
    ICLFTVSDDG HLVAQDPAEV TTVEGAGPRH MVFHPNEQYA YCVNELNSSV 200
    DVWELKDPHG NIECVQTLDM MPENFSDTRW AADIHITPDG RHLYACDRTA 250
    SLITVFSVSE DGSVLSKEGF QPTETQPRGF NVDHSGKYLI AAGQKSHHIS 300
    VYEIVGEQGL LHEKGRYAVG QGPMWVVVNA H 331
    Length:331
    Mass (Da):36,293
    Last modified:February 10, 2009 - v1
    Checksum:i457820D7279EAC52
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU928161 Genomic DNA. Translation: CAR02122.1.
    RefSeqiYP_002390586.1. NC_011742.1.

    Genome annotation databases

    EnsemblBacteriaiCAR02122; CAR02122; ECS88_0783.
    GeneIDi7130087.
    KEGGiecz:ECS88_0783.
    PATRICi18409280. VBIEscCol91599_0783.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU928161 Genomic DNA. Translation: CAR02122.1 .
    RefSeqi YP_002390586.1. NC_011742.1.

    3D structure databases

    ProteinModelPortali B7MGM4.
    SMRi B7MGM4. Positions 1-331.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 585035.ECS88_0783.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAR02122 ; CAR02122 ; ECS88_0783 .
    GeneIDi 7130087.
    KEGGi ecz:ECS88_0783.
    PATRICi 18409280. VBIEscCol91599_0783.

    Phylogenomic databases

    eggNOGi COG2706.
    HOGENOMi HOG000257418.
    KOi K07404.
    OMAi DKRFLYV.
    OrthoDBi EOG615VK7.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00409 .
    BioCyci ECOL585035:GJWP-788-MONOMER.

    Family and domain databases

    Gene3Di 2.130.10.10. 1 hit.
    HAMAPi MF_01605. 6P_gluconolactonase.
    InterProi IPR022528. 6-phosphogluconolactonase_YbhE.
    IPR019405. Lactonase_7-beta_prop.
    IPR011045. N2O_reductase_N.
    IPR015943. WD40/YVTN_repeat-like_dom.
    [Graphical view ]
    Pfami PF10282. Lactonase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50974. SSF50974. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: S88 / ExPEC.

    Entry informationi

    Entry namei6PGL_ECO45
    AccessioniPrimary (citable) accession number: B7MGM4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: February 10, 2009
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3