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Protein

Adenine deaminase

Gene

ade

Organism
Escherichia coli O45:K1 (strain S88 / ExPEC)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Adenine + H2O = hypoxanthine + NH3.UniRule annotation

Cofactori

Mn2+UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
LigandManganese

Names & Taxonomyi

Protein namesi
Recommended name:
Adenine deaminaseUniRule annotation (EC:3.5.4.2UniRule annotation)
Short name:
AdenaseUniRule annotation
Short name:
Adenine aminaseUniRule annotation
Gene namesi
Name:adeUniRule annotation
Ordered Locus Names:ECS88_4090
OrganismiEscherichia coli O45:K1 (strain S88 / ExPEC)
Taxonomic identifieri585035 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000747 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001462321 – 588Adenine deaminaseAdd BLAST588

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB7MFN5
SMRiB7MFN5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000276949
KOiK01486
OMAiHEIANVM

Family and domain databases

CDDicd01295 AdeC, 1 hit
Gene3Di2.30.40.10, 2 hits
HAMAPiMF_01518 Adenine_deamin, 1 hit
InterProiView protein in InterPro
IPR006679 Adenine_deam
IPR026912 Adenine_deam_C
IPR006680 Amidohydro-rel
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
PfamiView protein in Pfam
PF13382 Adenine_deam_C, 1 hit
PF01979 Amidohydro_1, 1 hit
SUPFAMiSSF51338 SSF51338, 2 hits
SSF51556 SSF51556, 1 hit
TIGRFAMsiTIGR01178 ade, 1 hit

Sequencei

Sequence statusi: Complete.

B7MFN5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNSINHKFH HISRTEYQEL LAVSRGDAVA DYIIDNVSIL DLINGGEISG
60 70 80 90 100
PIVIKGRYIA GVGAEYADAP ALQRIDARGA TAVPGFIDAH LHIESSMMTP
110 120 130 140 150
VTFETATLPR GLTTVICDPH EIVNVMGEAG FAWFARCAEQ ARQNQYLQVS
160 170 180 190 200
SCVPALEGCD VNGASFTLEQ MLAWRDHPQV TGLAEMMDYP GVISGQNALL
210 220 230 240 250
DKLDAFRHLT LDGHCPGLGG KELNAYIAAG IENCHESYQL EEGRRKLQLG
260 270 280 290 300
MSLMIREGSA ARNLNALAPL INEFNSPQCM LCTDDRNPWE IAHEGHIDAL
310 320 330 340 350
IRRLIEQHNV PLHVAYRVAS WSTARHFGLN HLGLLAPGKQ ADIVLLSDAR
360 370 380 390 400
KVTVQQVLVK GEPIDAQTLQ AEESARLAQS APPYGNTIDR QPVSASDFAL
410 420 430 440 450
QFTPGKRYRV IEVIHNELIT HSRSSVYSEN GFDRDDVCFI AVLERYGQRL
460 470 480 490 500
APACGLLGGF GLNEGALAAT VSHDSHNIVV IGRSAEEMAL AVNQVIQDGG
510 520 530 540 550
GLCVVRNGQV QSHLPLPIAG LMSTDTAQSL AEQIDALKAA ARECGPLPDE
560 570 580
PFIQMAFLSL PVIPALKLTS QGLFDGEKFA FTTLEFTE
Length:588
Mass (Da):63,851
Last modified:February 10, 2009 - v1
Checksum:iEF00812CDD92F402
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928161 Genomic DNA Translation: CAR05297.1
RefSeqiWP_001065732.1, NC_011742.1

Genome annotation databases

EnsemblBacteriaiCAR05297; CAR05297; ECS88_4090
KEGGiecz:ECS88_4090

Similar proteinsi

Entry informationi

Entry nameiADEC_ECO45
AccessioniPrimary (citable) accession number: B7MFN5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: March 28, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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