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B7MER5

- SYGA_ECO45

UniProt

B7MER5 - SYGA_ECO45

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Protein
Glycine--tRNA ligase alpha subunit
Gene
glyQ, ECS88_3977
Organism
Escherichia coli O45:K1 (strain S88 / ExPEC)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. glycine-tRNA ligase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. glycyl-tRNA aminoacylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciECOL585035:GJWP-3963-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycine--tRNA ligase alpha subunit (EC:6.1.1.14)
Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name:
GlyRS
Gene namesi
Name:glyQ
Ordered Locus Names:ECS88_3977
OrganismiEscherichia coli O45:K1 (strain S88 / ExPEC)
Taxonomic identifieri585035 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000747: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Glycine--tRNA ligase alpha subunitUniRule annotation
PRO_1000197192Add
BLAST

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits By similarity.

Protein-protein interaction databases

STRINGi585035.ECS88_3977.

Structurei

3D structure databases

ProteinModelPortaliB7MER5.
SMRiB7MER5. Positions 9-287.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0752.
HOGENOMiHOG000264291.
KOiK01878.
OMAiIQPLDME.
OrthoDBiEOG661H9S.

Family and domain databases

HAMAPiMF_00254. Gly_tRNA_synth_alpha.
InterProiIPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view]
PfamiPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSiPR01044. TRNASYNTHGA.
TIGRFAMsiTIGR00388. glyQ. 1 hit.
PROSITEiPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7MER5-1 [UniParc]FASTAAdd to Basket

« Hide

MQKFDTRTFQ GLILTLQDYW ARQGCTIVQP LDMEVGAGTS HPMTCLRALG    50
PEPMAAAYVQ PSRRPTDGRY GENPNRLQHY YQFQVVIKPS PDNIQELYLG 100
SLKELGMDPT IHDIRFVEDN WENPTLGAWG LGWEVWLNGM EVTQFTYFQQ 150
VGGLECKPVT GEITYGLERL AMYIQGVDSV YDLVWSDGPL GKTTYGDVFH 200
QNEVEQSTYN FEYADVDFLF TCFEQYEKEA QQLLALENPL PLPAYERILK 250
AAHSFNLLDA RKAISVTERQ RYILRIRTLT KAVAEAYYAS REALGFPMCN 300
KDK 303
Length:303
Mass (Da):34,716
Last modified:March 24, 2009 - v1
Checksum:i8C22062079FD4DDA
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU928161 Genomic DNA. Translation: CAR05186.1.
RefSeqiYP_002393548.1. NC_011742.1.

Genome annotation databases

EnsemblBacteriaiCAR05186; CAR05186; ECS88_3977.
GeneIDi7130043.
KEGGiecz:ECS88_3977.
PATRICi18415632. VBIEscCol91599_3906.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CU928161 Genomic DNA. Translation: CAR05186.1 .
RefSeqi YP_002393548.1. NC_011742.1.

3D structure databases

ProteinModelPortali B7MER5.
SMRi B7MER5. Positions 9-287.
ModBasei Search...

Protein-protein interaction databases

STRINGi 585035.ECS88_3977.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAR05186 ; CAR05186 ; ECS88_3977 .
GeneIDi 7130043.
KEGGi ecz:ECS88_3977.
PATRICi 18415632. VBIEscCol91599_3906.

Phylogenomic databases

eggNOGi COG0752.
HOGENOMi HOG000264291.
KOi K01878.
OMAi IQPLDME.
OrthoDBi EOG661H9S.

Enzyme and pathway databases

BioCyci ECOL585035:GJWP-3963-MONOMER.

Family and domain databases

HAMAPi MF_00254. Gly_tRNA_synth_alpha.
InterProi IPR006194. Gly-tRNA-synth_heterodimer.
IPR002310. Gly-tRNA_ligase_asu.
[Graphical view ]
Pfami PF02091. tRNA-synt_2e. 1 hit.
[Graphical view ]
PRINTSi PR01044. TRNASYNTHGA.
TIGRFAMsi TIGR00388. glyQ. 1 hit.
PROSITEi PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: S88 / ExPEC.

Entry informationi

Entry nameiSYGA_ECO45
AccessioniPrimary (citable) accession number: B7MER5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 24, 2009
Last modified: May 14, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi