Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B7MER5

- SYGA_ECO45

UniProt

B7MER5 - SYGA_ECO45

Protein

Glycine--tRNA ligase alpha subunit

Gene

glyQ

Organism
Escherichia coli O45:K1 (strain S88 / ExPEC)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (24 Mar 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).UniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. glycine-tRNA ligase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycyl-tRNA aminoacylation Source: InterPro

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciECOL585035:GJWP-3963-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glycine--tRNA ligase alpha subunitUniRule annotation (EC:6.1.1.14UniRule annotation)
    Alternative name(s):
    Glycyl-tRNA synthetase alpha subunitUniRule annotation
    Short name:
    GlyRSUniRule annotation
    Gene namesi
    Name:glyQUniRule annotation
    Ordered Locus Names:ECS88_3977
    OrganismiEscherichia coli O45:K1 (strain S88 / ExPEC)
    Taxonomic identifieri585035 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000747: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 303303Glycine--tRNA ligase alpha subunitPRO_1000197192Add
    BLAST

    Interactioni

    Subunit structurei

    Tetramer of two alpha and two beta subunits.UniRule annotation

    Protein-protein interaction databases

    STRINGi585035.ECS88_3977.

    Structurei

    3D structure databases

    ProteinModelPortaliB7MER5.
    SMRiB7MER5. Positions 9-287.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class-II aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0752.
    HOGENOMiHOG000264291.
    KOiK01878.
    OMAiIQPLDME.
    OrthoDBiEOG661H9S.

    Family and domain databases

    HAMAPiMF_00254. Gly_tRNA_synth_alpha.
    InterProiIPR006194. Gly-tRNA-synth_heterodimer.
    IPR002310. Gly-tRNA_ligase_asu.
    [Graphical view]
    PfamiPF02091. tRNA-synt_2e. 1 hit.
    [Graphical view]
    PRINTSiPR01044. TRNASYNTHGA.
    TIGRFAMsiTIGR00388. glyQ. 1 hit.
    PROSITEiPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B7MER5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQKFDTRTFQ GLILTLQDYW ARQGCTIVQP LDMEVGAGTS HPMTCLRALG    50
    PEPMAAAYVQ PSRRPTDGRY GENPNRLQHY YQFQVVIKPS PDNIQELYLG 100
    SLKELGMDPT IHDIRFVEDN WENPTLGAWG LGWEVWLNGM EVTQFTYFQQ 150
    VGGLECKPVT GEITYGLERL AMYIQGVDSV YDLVWSDGPL GKTTYGDVFH 200
    QNEVEQSTYN FEYADVDFLF TCFEQYEKEA QQLLALENPL PLPAYERILK 250
    AAHSFNLLDA RKAISVTERQ RYILRIRTLT KAVAEAYYAS REALGFPMCN 300
    KDK 303
    Length:303
    Mass (Da):34,716
    Last modified:March 24, 2009 - v1
    Checksum:i8C22062079FD4DDA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU928161 Genomic DNA. Translation: CAR05186.1.
    RefSeqiYP_002393548.1. NC_011742.1.

    Genome annotation databases

    EnsemblBacteriaiCAR05186; CAR05186; ECS88_3977.
    GeneIDi7130043.
    KEGGiecz:ECS88_3977.
    PATRICi18415632. VBIEscCol91599_3906.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CU928161 Genomic DNA. Translation: CAR05186.1 .
    RefSeqi YP_002393548.1. NC_011742.1.

    3D structure databases

    ProteinModelPortali B7MER5.
    SMRi B7MER5. Positions 9-287.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 585035.ECS88_3977.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAR05186 ; CAR05186 ; ECS88_3977 .
    GeneIDi 7130043.
    KEGGi ecz:ECS88_3977.
    PATRICi 18415632. VBIEscCol91599_3906.

    Phylogenomic databases

    eggNOGi COG0752.
    HOGENOMi HOG000264291.
    KOi K01878.
    OMAi IQPLDME.
    OrthoDBi EOG661H9S.

    Enzyme and pathway databases

    BioCyci ECOL585035:GJWP-3963-MONOMER.

    Family and domain databases

    HAMAPi MF_00254. Gly_tRNA_synth_alpha.
    InterProi IPR006194. Gly-tRNA-synth_heterodimer.
    IPR002310. Gly-tRNA_ligase_asu.
    [Graphical view ]
    Pfami PF02091. tRNA-synt_2e. 1 hit.
    [Graphical view ]
    PRINTSi PR01044. TRNASYNTHGA.
    TIGRFAMsi TIGR00388. glyQ. 1 hit.
    PROSITEi PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: S88 / ExPEC.

    Entry informationi

    Entry nameiSYGA_ECO45
    AccessioniPrimary (citable) accession number: B7MER5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: March 24, 2009
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3