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B7MB25 (UXAC_ECO45) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Uronate isomerase

EC=5.3.1.12
Alternative name(s):
Glucuronate isomerase
Uronic isomerase
Gene names
Name:uxaC
Ordered Locus Names:ECS88_3488
OrganismEscherichia coli O45:K1 (strain S88 / ExPEC) [Complete proteome] [HAMAP]
Taxonomic identifier585035 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length470 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucuronate = D-fructuronate. HAMAP-Rule MF_00675

D-galacturonate = D-tagaturonate. HAMAP-Rule MF_00675

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP-Rule MF_00675

Sequence similarities

Belongs to the uronate isomerase family.

Ontologies

Keywords
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglucuronate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 470470Uronate isomerase HAMAP-Rule MF_00675
PRO_1000131588

Sequences

Sequence LengthMass (Da)Tools
B7MB25 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: 9E51AA7B88411281

FASTA47053,987
        10         20         30         40         50         60 
MTPFMTEDFL LDTEFARRLY HDYAKDQPIF DYHCHLPPQQ IAEDYRFKNL YDIWLKGDHY 

        70         80         90        100        110        120 
KWRAMRTNGV AERLCTGDAS DREKFDAWAA TVPHTIGNPL YHWTHLELRR PFGITGKLLS 

       130        140        150        160        170        180 
PSTADEIWNE CNELLAQDNF SARGIMQQMN VKMVGTTDDP IDSLEHHAEI AKDGSFTIKV 

       190        200        210        220        230        240 
LPSWRPDKAF NIEQATFNDY MAKLGEVSDT DIRRFADLQT ALTKRLDHFA AHGCKVSDHA 

       250        260        270        280        290        300 
LDVVMFAEAN EAELDSILAR RLAGETLSEH EVAQFKTAVL VFLGAEYARR GWVQQYHIGA 

       310        320        330        340        350        360 
LRNNNLRQFK LLGPDVGFDS INDRPMAEEL SKLLSKQNEE NLLPKTILYC LNPRDNEVLG 

       370        380        390        400        410        420 
TMIGNFQGEG MPGKMQFGSG WWFNDQKDGM ERQMTQLAQL GLLSRFVGML TDSRSFLSYT 

       430        440        450        460        470 
RHEYFRRILC QMIGRWVEAG EAPADINLLG EMVKNICFNN ARDYFAIELN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU928161 Genomic DNA. Translation: CAR04716.1.
RefSeqYP_002393089.1. NC_011742.1.

3D structure databases

ProteinModelPortalB7MB25.
SMRB7MB25. Positions 4-468.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING585035.ECS88_3488.

Proteomic databases

PRIDEB7MB25.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAR04716; CAR04716; ECS88_3488.
GeneID7132463.
KEGGecz:ECS88_3488.
PATRIC18414636. VBIEscCol91599_3419.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1904.
HOGENOMHOG000224075.
KOK01812.
OMAGHTDPRW.
OrthoDBEOG6J1D95.
ProtClustDBPRK02925.

Enzyme and pathway databases

BioCycECOL585035:GJWP-3475-MONOMER.
UniPathwayUPA00246.

Family and domain databases

Gene3D1.10.2020.10. 1 hit.
HAMAPMF_00675. UxaC.
InterProIPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamPF02614. UxaC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUXAC_ECO45
AccessionPrimary (citable) accession number: B7MB25
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: February 19, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways