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Protein

Ribosomal RNA small subunit methyltransferase G

Gene

rsmG

Organism
Escherichia coli O8 (strain IAI1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N7-methylguanine(527) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei73S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation1
Binding sitei78S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation1
Binding sitei139S-adenosyl-L-methionineUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferase, Transferase
Biological processrRNA processing
LigandS-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase GUniRule annotation (EC:2.1.1.170UniRule annotation)
Alternative name(s):
16S rRNA 7-methylguanosine methyltransferaseUniRule annotation
Short name:
16S rRNA m7G methyltransferaseUniRule annotation
Gene namesi
Name:rsmGUniRule annotation
Ordered Locus Names:ECIAI1_3924
OrganismiEscherichia coli O8 (strain IAI1)
Taxonomic identifieri585034 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001170681 – 207Ribosomal RNA small subunit methyltransferase GAdd BLAST207

Structurei

3D structure databases

ProteinModelPortaliB7M596
SMRiB7M596
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni124 – 125S-adenosyl-L-methionine bindingUniRule annotation2

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000221012
KOiK03501
OMAiYPRKAGI

Family and domain databases

HAMAPiMF_00074 16SrRNA_methyltr_G, 1 hit
InterProiView protein in InterPro
IPR003682 rRNA_ssu_MeTfrase_G
IPR029063 SAM-dependent_MTases
PANTHERiPTHR31760 PTHR31760, 1 hit
PfamiView protein in Pfam
PF02527 GidB, 1 hit
PIRSFiPIRSF003078 GidB, 1 hit
SUPFAMiSSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00138 rsmG_gidB, 1 hit

Sequencei

Sequence statusi: Complete.

B7M596-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNKLSLLLK DAGISLTDHQ KNQLIAYVNM LHKWNKAYNL TSVRDPNEML
60 70 80 90 100
VRHILDSIVV APYLQGERFI DVGTGPGLPG IPLSIVRPEA HFTLLDSLGK
110 120 130 140 150
RVRFLRQVQH ELKLENIEPV QSRVEEFPSE PPFDGVISRA FASLNDMVSW
160 170 180 190 200
CHHLPGEQGR FYALKGQMPE DEIALLPEEY QVESVVKLQV PALDGERHLV

VIKANKI
Length:207
Mass (Da):23,431
Last modified:March 24, 2009 - v1
Checksum:i40CF9BA134E9A234
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928160 Genomic DNA Translation: CAR00718.1
RefSeqiWP_000932839.1, NC_011741.1

Genome annotation databases

EnsemblBacteriaiCAR00718; CAR00718; ECIAI1_3924
KEGGiecr:ECIAI1_3924

Similar proteinsi

Entry informationi

Entry nameiRSMG_ECO8A
AccessioniPrimary (citable) accession number: B7M596
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 24, 2009
Last modified: June 7, 2017
This is version 53 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health