B7LZE8 (B7LZE8_ECO8A) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hydrogenase 2, large subunit EMBL CAQ99958.1
EC=1.12.7.2 EMBL CAQ99958.1

Gene names

Name:	hybC EMBL CAQ99958.1
Ordered Locus Names:	ECIAI1_3143

Organism

Escherichia coli O8 (strain IAI1) [Complete proteome] [HAMAP]

Taxonomic identifier

585034 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	567 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. RuleBase RU003896

Ontologies

Keywords
Ligand	Metal-binding RuleBase RU003896 Nickel RuleBase RU003896
Molecular function	Oxidoreductase RuleBase RU003896 EMBL CAQ99958.1
Technical term	Complete proteome
Gene Ontology (GO)
Molecular_function	ferredoxin hydrogenase activity Inferred from electronic annotation. Source: EC nickel cation binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7LZE8 [UniParc]. Last modified March 24, 2009. Version 1. Checksum: A19E6F513390F29E	FASTA	567	62,491
	10 20 30 40 50 60 MSQRITIDPV TRIEGHLRID CEIENGVVSK AWASGTMWRG MEEIVKNRDP RDAWMIVQRI 70 80 90 100 110 120 CGVCTTTHAL SSVRAAESAL NIDVPVNAQY IRNIILAAHT THDHIVHFYQ LSALDWVDIT 130 140 150 160 170 180 SALQADPTKA SEMLKGVSTW HLNSPEEFTK VQNKIKDLVA SGQLGIFANG YWGHPAMKLP 190 200 210 220 230 240 PEVNLIAVAH YLQALECQRD ANRVVALLGG KTPHIQNLAV GGVANPINLD GLGVLNLERL 250 260 270 280 290 300 MYIKSFIDKL SDFVEQVYKV DTAVIAAFYP EWLTRGKGAV NYLSVPEFPT DSKNGSFLFP 310 320 330 340 350 360 GGYIENADLS SYRPITSHSD EYLIKGIQES AKHSWYKDEA PQAPWEGTTI PAYDGWSDDG 370 380 390 400 410 420 KYSWVKSPTF YGKTVEVGPL ANMLVKLAAG RESTQNKLNE IVAIYQKLTG NTLEVAQLHS 430 440 450 460 470 480 TLGRIIGRTV HCCELQDILQ NQYSALITNI GKGDHTTFVK PNIPATGEFK GVGFLEAPRG 490 500 510 520 530 540 MLSHWMVIKD GIISNYQAVV PSTWNSGPRN FNDDVGPYEQ SLVGTPVADP NKPLEVVRTI 550 560 HSFDPCMACA VHVVDADGNE VVSVKVL

References

[1]

"Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths." Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P., Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H., Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E. , Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C., Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S., Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J., Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E. PLoS Genet. 5:E1000344-E1000344(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: IAI1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU928160 Genomic DNA. Translation: CAQ99958.1.
RefSeq	YP_002388481.1. NC_011741.1.
3D structure databases
ProteinModelPortal	B7LZE8.
SMR	B7LZE8. Positions 5-552.
ModBase	Search...
Protein-protein interaction databases
STRING	585034.ECIAI1_3143.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAQ99958; CAQ99958; ECIAI1_3143.
GeneID	7125335.
KEGG	ecr:ECIAI1_3143.
PATRIC	18325559. VBIEscCol26572_3082.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0374.
HOGENOM	HOG000278799.
KO	K06281.
OMA	VHFYHLS.
ProtClustDB	PRK10467.
Enzyme and pathway databases
BioCyc	ECOL585034:GJ84-3178-MONOMER.
Family and domain databases
InterPro	IPR001501. Ni-dep_hyd_lsu. IPR018194. Ni-dep_hyd_lsu_Ni_BS. [Graphical view]
Pfam	PF00374. NiFeSe_Hases. 1 hit. [Graphical view]
PROSITE	PS00507. NI_HGENASE_L_1. 1 hit. PS00508. NI_HGENASE_L_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B7LZE8_ECO8A

Accession

Primary (citable) accession number: B7LZE8

Entry history

Integrated into UniProtKB/TrEMBL:	March 24, 2009
Last sequence update:	March 24, 2009
Last modified:	May 1, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)