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Protein

2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase

Gene

citG

Organism
Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A, the precursor of the prosthetic group of the holo-acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA.UniRule annotation

Catalytic activityi

ATP + 3'-dephospho-CoA = 2'-(5-triphospho-alpha-D-ribosyl)-3'-dephospho-CoA + adenine.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthaseUniRule annotation (EC:2.4.2.52UniRule annotation)
Short name:
2-(5''-triphosphoribosyl)-3'-dephospho-CoA synthaseUniRule annotation
Gene namesi
Name:citGUniRule annotation
Ordered Locus Names:EFER_0037
OrganismiEscherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Taxonomic identifieri585054 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000745 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001232251 – 3032-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthaseAdd BLAST303

Family & Domainsi

Sequence similaritiesi

Belongs to the CitG/MdcB family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000258582.
KOiK05966.
OMAiHADMDAD.
OrthoDBiPOG091H0I1L.

Family and domain databases

HAMAPiMF_00397. CitG. 1 hit.
InterProiIPR002736. CitG.
IPR017551. TriPribosyl-deP-CoA_syn_CitG.
[Graphical view]
PfamiPF01874. CitG. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03125. citrate_citG. 1 hit.

Sequencei

Sequence statusi: Complete.

B7LWM0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDVITTDQP ASATSLLQAK GIANLVERAL LTEVRLTPKP GLVDIRNSGA
60 70 80 90 100
HKDMDLALFE KSTLAVAPWM ENFYQLGYDT SALEAELVLP MLRPIGMACE
110 120 130 140 150
ADMLQATGGV NTHRGAVFSF GLISAVTGRM VALEEELEQN RICYWVARMC
160 170 180 190 200
RDLVAKELSS EATNAATSKS VEHFLHYGLS GARGEAESGF QTVRTVALPI
210 220 230 240 250
FERIRAQNED MNLALLQTLL HLMAWNNDTN LVSRGALKGL YYVQQQAQKM
260 270 280 290 300
LWEGGVLMRG GLEALQAFDD ELIARNLSPG GSADLLAVTW FLSHFPKGET

FAD
Length:303
Mass (Da):33,180
Last modified:February 10, 2009 - v1
Checksum:i97E669FD4E7A5DD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928158 Genomic DNA. Translation: CAQ87623.1.
RefSeqiWP_001286124.1. NC_011740.1.

Genome annotation databases

EnsemblBacteriaiCAQ87623; CAQ87623; EFER_0037.
KEGGiefe:EFER_0037.
PATRICi32124497. VBIEscFer122920_0037.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928158 Genomic DNA. Translation: CAQ87623.1.
RefSeqiWP_001286124.1. NC_011740.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAQ87623; CAQ87623; EFER_0037.
KEGGiefe:EFER_0037.
PATRICi32124497. VBIEscFer122920_0037.

Phylogenomic databases

HOGENOMiHOG000258582.
KOiK05966.
OMAiHADMDAD.
OrthoDBiPOG091H0I1L.

Family and domain databases

HAMAPiMF_00397. CitG. 1 hit.
InterProiIPR002736. CitG.
IPR017551. TriPribosyl-deP-CoA_syn_CitG.
[Graphical view]
PfamiPF01874. CitG. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03125. citrate_citG. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiCITG_ESCF3
AccessioniPrimary (citable) accession number: B7LWM0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: November 2, 2016
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.