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Protein

DNA mismatch repair protein MutH

Gene

mutH

Organism
Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.UniRule annotationSAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonucleaseUniRule annotationSAAS annotation, Hydrolase, Nuclease
Biological processDNA damage, DNA repairUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutHUniRule annotationSAAS annotation
Alternative name(s):
Methyl-directed mismatch repair proteinUniRule annotation
Gene namesi
Name:mutHUniRule annotationImported
Ordered Locus Names:EFER_2764Imported
OrganismiEscherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)Imported
Taxonomic identifieri585054 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000745 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 160MutHInterPro annotationAdd BLAST99

Sequence similaritiesi

Belongs to the MutH family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000271839.
KOiK03573.
OMAiPPDLKRD.
OrthoDBiPOG091H04RA.

Family and domain databases

CDDicd00583. MutH_Sau3AI. 1 hit.
Gene3Di3.40.600.10. 1 hit.
HAMAPiMF_00759. MutH. 1 hit.
InterProiView protein in InterPro
IPR004230. DNA_mismatch_repair_MutH.
IPR011337. DNA_rep_MutH/RE_typeII.
IPR037057. DNA_rep_MutH/RE_typeII_sf.
IPR011335. Restrct_endonuc-II-like.
PfamiView protein in Pfam
PF02976. MutH. 1 hit.
SMARTiView protein in SMART
SM00927. MutH. 1 hit.
SUPFAMiSSF52980. SSF52980. 1 hit.
TIGRFAMsiTIGR02248. mutH_TIGR. 1 hit.

Sequencei

Sequence statusi: Complete.

B7LNI6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNSMPDIRPL LTSPASEAEL LAQAQQLSGY TLGELAALAG MVTPKDLKRD
60 70 80 90 100
KGWIGVLLEI WLGASAGSKP EQDFAALGVE LKTIPVDSLG RPLETTFVCV
110 120 130 140 150
APLTGNTGVT WETSHVRHKL KRVLWIPVEG ERSIPLAQRR VGSPLLWSPN
160 170 180 190 200
EEEDRQLRLD WEELMDMIVL GRVERITARH GEVLQLRPKA ANAKALTEAI
210 220 230
GANGEPILTL PRGFYLKKNF TSALLARHFL IQQP
Length:234
Mass (Da):25,824
Last modified:February 10, 2009 - v1
Checksum:i1413265855FF5933
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928158 Genomic DNA. Translation: CAQ90259.1.

Genome annotation databases

EnsemblBacteriaiCAQ90259; CAQ90259; EFER_2764.
KEGGiefe:EFER_2764.

Similar proteinsi

Entry informationi

Entry nameiB7LNI6_ESCF3
AccessioniPrimary (citable) accession number: B7LNI6
Entry historyiIntegrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: October 25, 2017
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported