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Protein

Uronate isomerase

Gene

uxaC

Organism
Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

UniPathwayiUPA00246.

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:EFER_4383
OrganismiEscherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)
Taxonomic identifieri585054 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000745 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001315961 – 470Uronate isomeraseAdd BLAST470

Structurei

3D structure databases

ProteinModelPortaliB7LMX3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the uronate isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiREMTTET.
OrthoDBiPOG091H07GL.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.

Sequencei

Sequence statusi: Complete.

B7LMX3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPFMTEDFL LDTEFARRLY HEYAKDQPIF DYHCHLPPQQ IAEDYRFKNL
60 70 80 90 100
YDIWLKGDHY KWRAMRTNGV AERLCTGDAS DREKFDAWAA TVPHTIGNPL
110 120 130 140 150
YHWTHLELRR PFGITGKLLS PSTADEIWNQ CNELLAQDNF SARGIMQQMN
160 170 180 190 200
VKMVGTTDDP IDSLEHHAEI AKDGSFTIKV LPSWRPDKAF NIEQATFNDY
210 220 230 240 250
MAKLGEVSDT DIRRFADLQT ALTKRLDHFA AHGCKVSDHA LDVVMFAEAN
260 270 280 290 300
EAELDSILAR RLAGETLSEH EVAQFKTAVL VFLGAEYARR GWVQQYHIGA
310 320 330 340 350
LRNNNLRQFK LLGPDVGFDS INDRPMAEEL SKLLSKQNEE NLLPKTILYC
360 370 380 390 400
LNPRDNEVLG TMIGNFQGEG MPGKMQFGSG WWFNDQKDGM ERQMTQLAQL
410 420 430 440 450
GLLSRFVGML TDSRSFLSYT RHEYFRRILC QMIGRWVEAG EAPADINLLG
460 470
EMVKNICFNN ARDYFAIELN
Length:470
Mass (Da):54,000
Last modified:February 10, 2009 - v1
Checksum:i491EF31DB17D0E9D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928158 Genomic DNA. Translation: CAQ91801.1.
RefSeqiWP_000187461.1. NC_011740.1.

Genome annotation databases

EnsemblBacteriaiCAQ91801; CAQ91801; EFER_4383.
KEGGiefe:EFER_4383.
PATRICi32133076. VBIEscFer122920_4219.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928158 Genomic DNA. Translation: CAQ91801.1.
RefSeqiWP_000187461.1. NC_011740.1.

3D structure databases

ProteinModelPortaliB7LMX3.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAQ91801; CAQ91801; EFER_4383.
KEGGiefe:EFER_4383.
PATRICi32133076. VBIEscFer122920_4219.

Phylogenomic databases

HOGENOMiHOG000224075.
KOiK01812.
OMAiREMTTET.
OrthoDBiPOG091H07GL.

Enzyme and pathway databases

UniPathwayiUPA00246.

Family and domain databases

Gene3Di1.10.2020.10. 1 hit.
HAMAPiMF_00675. UxaC. 1 hit.
InterProiIPR032466. Metal_Hydrolase.
IPR003766. Uronate_isomerase.
IPR023177. Uronate_isomerase_dom2.
[Graphical view]
PfamiPF02614. UxaC. 1 hit.
[Graphical view]
SUPFAMiSSF51556. SSF51556. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_ESCF3
AccessioniPrimary (citable) accession number: B7LMX3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: November 2, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.