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B7LM93 (B7LM93_ESCF3) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonucleoside-diphosphate reductase RuleBase RU003410
EC=1.17.4.1 RuleBase RU003410
Gene names
Name:nrdA EMBL CAQ88466.1
Ordered Locus Names:EFER_0931 EMBL CAQ88466.1
OrganismEscherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) [Complete proteome] [HAMAP] EMBL CAQ88466.1
Taxonomic identifier585054 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length761 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides By similarity. RuleBase RU003410

Catalytic activity

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. RuleBase RU003410

Pathway

Genetic information processing; DNA replication. RuleBase RU003410

Sequence similarities

Belongs to the ribonucleoside diphosphate reductase large chain family. RuleBase RU003410

Sequences

Sequence LengthMass (Da)Tools
B7LM93 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: 5339EEB19567D9F8

FASTA76185,735
        10         20         30         40         50         60 
MNQNLLVTKR DGSTERINLD KIHRVLDWAA EGLHNVSISQ VELRSHIQFY DGIKTSDIHE 

        70         80         90        100        110        120 
TIIKAAADLI SRDAPDYQYL AARLAIFHLR KKAYGQFEPP ALYDHVVKMV EMGKYDNHLL 

       130        140        150        160        170        180 
EDYTEEEFKQ MDTFIDHDRD MTFSYAAVKQ LEGKYLVQNR VTGEIYESAQ FLYILVAACL 

       190        200        210        220        230        240 
FSNYPRETRL QYVKRFYDAV STFKISLPTP IMSGVRTPTR QFSSCVLIEC GDSLDSINAT 

       250        260        270        280        290        300 
SSAIVKYVSQ RAGIGINAGR IRALGSPIRG GEAFHTGCIP FYKHFQTAVK SCSQGGVRGG 

       310        320        330        340        350        360 
AATLFYPMWH LEVESLLVLK NNRGVEGNRV RHMDYGVQIN KLMYTRLLKG EDITLFSPSD 

       370        380        390        400        410        420 
VPGLYDAFFA DQEEFERLYT KYEKDDSIRK QRVKAVDLFS LMMQERASTG RIYIQNVDHC 

       430        440        450        460        470        480 
NTHSPFDPAI APVRQSNLCL EIALPTKPLN DVNDENGEIA LCTLSAFNLG AINSLDELEE 

       490        500        510        520        530        540 
LAILAVRALD ALLDYQDYPI PAAKRGAMGR RTLGIGVINF AYYLAKHGKR YSDGSANNLT 

       550        560        570        580        590        600 
HKTFEAIQYY LLKASNELAK EQGACPWFNE TTYAKGILPI DTYKKDLDAI ANEQLHYDWE 

       610        620        630        640        650        660 
ALRESIKTHG LRNSTLSALM PSETSSQISN ATNGIEPPRG YVSIKASKDG ILRQVVPDYE 

       670        680        690        700        710        720 
HLHDAYELLW EMPGNDGYLQ LVGIMQKFID QSISANTNYD PSRFPSGKVP MQQLLKDLLT 

       730        740        750        760 
AYKFGVKTLY YQNTRDGAED AQDDLVPSIQ DDGCESGACK I

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CU928158 Genomic DNA. Translation: CAQ88466.1.
RefSeqYP_002382103.1. NC_011740.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING585054.EFER_0931.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAQ88466; CAQ88466; EFER_0931.
GeneID7119659.
KEGGefe:EFER_0931.
PATRIC32126269. VBIEscFer122920_0896.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0209.
HOGENOMHOG000278076.
KOK00525.
ProtClustDBPRK09103.

Enzyme and pathway databases

BioCycEFER585054:GJJM-925-MONOMER.
UniPathwayUPA00326.

Family and domain databases

InterProIPR005144. ATP-cone.
IPR013346. NrdE_NrdA.
IPR000788. RNR_lg_C.
IPR013509. RNR_lsu_N.
IPR008926. RNR_R1-su_N.
[Graphical view]
PfamPF03477. ATP-cone. 1 hit.
PF02867. Ribonuc_red_lgC. 1 hit.
PF00317. Ribonuc_red_lgN. 1 hit.
[Graphical view]
PRINTSPR01183. RIBORDTASEM1.
SUPFAMSSF48168. Ribonucleo_red_N. 1 hit.
TIGRFAMsTIGR02506. NrdE_NrdA. 1 hit.
PROSITEPS51161. ATP_CONE. 1 hit.
PS00089. RIBORED_LARGE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB7LM93_ESCF3
AccessionPrimary (citable) accession number: B7LM93
Entry history
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: May 1, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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