B7LKT9 (B7LKT9_ESCF3) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Asparagine synthetase PIRNR PIRNR001589
EC=6.3.5.4 PIRNR PIRNR001589

Gene names

Name:	asnB EMBL CAQ89934.1
Ordered Locus Names:	EFER_2435 EMBL CAQ89934.1

Organism

Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) [Complete proteome] [HAMAP] EMBL CAQ89934.1

Taxonomic identifier

585054 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia fergusonii

Protein attributes

Sequence length	554 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	ATP + L-aspartate + L-glutamine + H2O = AMP + diphosphate + L-asparagine + L-glutamate. PIRNR PIRNR001589
Pathway	Amino-acid biosynthesis; L-asparagine biosynthesis. PIRNR PIRNR001589

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Asparagine biosynthesis PIRNR PIRNR001589
Ligand	ATP-binding PIRNR PIRNR001589 Nucleotide-binding
Molecular function	Ligase PIRNR PIRNR001589 EMBL CAQ89934.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	L-asparagine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW asparagine synthase (glutamine-hydrolyzing) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7LKT9 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 9083B264EECC9F5C	FASTA	554	62,675
	10 20 30 40 50 60 MCSIFGVFDI KTDAVELRKK ALELSRLMRH RGPDWSGIYA SDNAILAHER LSIVDVNAGA 70 80 90 100 110 120 QPLYNQQKTH VLAVNGEIYN HQALRAEYGD RYQFQTGSDC EVILALYQEK GPEFLDDLQG 130 140 150 160 170 180 MFAFALYDSE KDAYLIGRDH LGIIPLYMGY DEHGQLYVAS EMKALVPVCR TIKEFPAGSY 190 200 210 220 230 240 LWSQDGEIRS YYHRDWFDYD AVKDNVTDKN ELRQALEDSV KSHLMSDVPY GVLLSGGLDS 250 260 270 280 290 300 SIISAITKKY AARRVEDQER SEAWWPQLHS FAVGLPGSPD LKAAQEVANH LGTVHHEIHF 310 320 330 340 350 360 TVQEGLDAIR DVIYHIETYD VTTIRASTPM YLMSRKIKAM GIKMVLSGEG SDEVFGGYLY 370 380 390 400 410 420 FHKAPNAKEL HEETVRKLLA LHMYDCARAN KAMSAWGVEA RVPFLDKKFL DVAMRINPQD 430 440 450 460 470 480 KMCGNGKMEK HILRECFESY LPASVAWRQK EQFSDGVGYS WIDTLKEVAA QQVSDQQLET 490 500 510 520 530 540 ARFRFPYNTP TSKEAYLYRE IFEELFPLPS AAECVPGGPS VACSSAKAIE WDEAFKKMDD 550 PSGRAVGVHQ SAYK

References

[1]

"Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths." Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P., Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H., Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E. , Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C., Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S., Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J., Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E. PLoS Genet. 5:E1000344-E1000344(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35469 / DSM 13698 / CDC 0568-73.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU928158 Genomic DNA. Translation: CAQ89934.1.
RefSeq	YP_002383549.1. NC_011740.1.
3D structure databases
ProteinModelPortal	B7LKT9.
SMR	B7LKT9. Positions 3-517.
ModBase	Search...
Protein-protein interaction databases
STRING	585054.EFER_2435.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAQ89934; CAQ89934; EFER_2435.
GeneID	7120663.
KEGG	efe:EFER_2435.
PATRIC	32129234. VBIEscFer122920_2353.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0367.
HOGENOM	HOG000027493.
KO	K01953.
ProtClustDB	PRK09431.
Enzyme and pathway databases
BioCyc	EFER585054:GJJM-2434-MONOMER.
UniPathway	UPA00134.
Family and domain databases
Gene3D	3.40.50.620. 1 hit.
InterPro	IPR006426. Asn_synth_AEB. IPR001962. Asn_synthase. IPR017932. GATase_2_dom. IPR000583. GATase_dom. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Pfam	PF00733. Asn_synthase. 1 hit. PF13537. GATase_7. 1 hit. [Graphical view]
PIRSF	PIRSF001589. Asn_synthetase_glu-h. 1 hit.
TIGRFAMs	TIGR01536. asn_synth_AEB. 1 hit.
PROSITE	PS51278. GATASE_TYPE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B7LKT9_ESCF3

Accession

Primary (citable) accession number: B7LKT9

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	May 1, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)