Potassium-transporting ATPase B chain - Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73)

Preferred order of sections

Names and origin

Protein names

Recommended name:
Potassium-transporting ATPase B chain
EC=3.6.3.12

Alternative name(s):
ATP phosphohydrolase [potassium-transporting] B chain
Potassium-binding and translocating subunit B
Potassium-translocating ATPase B chain

Gene names

Name:	kdpB
Ordered Locus Names:	EFER_2413

Organism

Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) [Complete proteome] [HAMAP]

Taxonomic identifier

585054 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia ›

Protein attributes

Sequence length	682 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions By similarity. HAMAP-Rule MF_00285
Catalytic activity	ATP + H₂O + K⁺(Out) = ADP + phosphate + K⁺(In). HAMAP-Rule MF_00285
Subcellular location	Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_00285.
Sequence similarities	Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. [View classification]

Ontologies

Keywords
Biological process	Ion transport Potassium transport Transport
Cellular component	Cell inner membrane Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Ligand	ATP-binding Magnesium Metal-binding Nucleotide-binding Potassium
Molecular function	Hydrolase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP potassium-transporting ATPase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 682

682

Potassium-transporting ATPase B chain HAMAP-Rule MF_00285

PRO_1000119413

Regions

Transmembrane

34 – 54

21

Helical; Potential

Transmembrane

62 – 82

21

Helical; Potential

Transmembrane

219 – 239

21

Helical; Potential

Transmembrane

254 – 274

21

Helical; Potential

Transmembrane

588 – 608

21

Helical; Potential

Transmembrane

616 – 636

21

Helical; Potential

Transmembrane

656 – 676

21

Helical; Potential

Sites

Active site

307

1

4-aspartylphosphate intermediate By similarity

Metal binding

518

1

Magnesium By similarity

Metal binding

522

1

Magnesium By similarity

Sequences

Sequence

Length

Mass (Da)

Tools

B7LKR7 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: D85360FD27E55AD9
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FASTA

682

72,266

        10         20         30         40         50         60 
MSRKQLALFE PTLVVQALKE AVKKLNPQAQ WRNPVMFIVW IGSLLTTCIS IAMASGAMPG 

        70         80         90        100        110        120 
NALFSAAISG WLWVTVLFAN FAEALAEGRS KAQANSLKGV KKTAFARKLR EPKYGAAADK 

       130        140        150        160        170        180 
VPADQLRKGD IVLVEAGDII PCDGEVIEGG ASVDESAITG ESAPVIRESG GDFASVTGGT 

       190        200        210        220        230        240 
RILSDWLVIE CSVNPGETFL DRMIAMVEGA QRRKTPNEIA LTILLIALTI VFLLATATLW 

       250        260        270        280        290        300 
PFSAWGGNAV SVTVLVALLV CLIPTTIGGL LSAIGVAGMS RMLGTNVIAT SGRAVEAAGD 

       310        320        330        340        350        360 
VDVLLLDKTG TITLGNRQAS EFIPAQGVEE KTLADAAQLA SLADETPEGR SIVILAKQRF 

       370        380        390        400        410        420 
NLRERDVQSL HATFVPFTAQ SRMSGINIDN RMIRKGSVDA IRRHIEANGG HFPADVDQKV 

       430        440        450        460        470        480 
DQVARQGATP LVVVEGSRVL GVIALKDIVK GGIKERFAQL RQMGIKTVMI TGDNRLTAAA 

       490        500        510        520        530        540 
IAAEAGVDDF LAEATPEAKL ALIRQYQAEG RLVAMTGDGT NDAPALAQAD VAVAMNSGTQ 

       550        560        570        580        590        600 
AAKEAGNMVD LDSNPTKLIE VVHIGKQMLM TRGSLTTFSI ANDVAKYFAI IPAAFAATYP 

       610        620        630        640        650        660 
QLNALNIMRL HSPDSAILSA VIFNALIIVF LIPLALKGVS YKPLTASAML RRNLWIYGLG 

       670        680 
GLLVPFIGIK VIDLLLTVCG LV

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References

[1]

"Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths."
Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P., Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H., Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.

Denamur E.
PLoS Genet. 5:E1000344-E1000344(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 35469 / DSM 13698 / CDC 0568-73.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU928158 Genomic DNA. Translation: CAQ89912.1.
RefSeq	YP_002383527.1. NC_011740.1.
3D structure databases
ProteinModelPortal	B7LKR7.
ModBase	Search...
Protein-protein interaction databases
STRING	585054.EFER_2413.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAQ89912; CAQ89912; EFER_2413.
GeneID	7120805.
KEGG	efe:EFER_2413.
PATRIC	32129186. VBIEscFer122920_2329.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2216.
HOGENOM	HOG000244113.
KO	K01547.
ProtClustDB	PRK01122.
Enzyme and pathway databases
BioCyc	EFER585054:GJJM-2412-MONOMER.
Family and domain databases
Gene3D	2.70.150.10. 1 hit. 3.40.1110.10. 1 hit. 3.40.50.1000. 1 hit.
HAMAP	MF_00285. KdpB.
InterPro	IPR023299. ATPase_P-typ_cyto_domN. IPR018303. ATPase_P-typ_P_site. IPR008250. ATPase_P-typ_transduc_dom_A. IPR001757. Cation_transp_P_typ_ATPase. IPR023214. HAD-like_dom. IPR006391. K-transp_ATPase_bsu_IA. [Graphical view]
PANTHER	PTHR24093. PTHR24093. 1 hit.
Pfam	PF00122. E1-E2_ATPase. 1 hit. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE.
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01494. ATPase_P-type. 2 hits. TIGR01497. kdpB. 1 hit.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATKB_ESCF3

Accession

Primary (citable) accession number: B7LKR7

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 14, 2009
Last sequence update:	February 10, 2009
Last modified:	May 1, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sites

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

Entry information

Relevant documents