B7LH61 (B7LH61_ECO55) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Tartronate semialdehyde reductase EMBL CAU99722.1
EC=1.1.1.60 EMBL CAU99722.1

Gene names

Name:	garR EMBL CAU99722.1
Ordered Locus Names:	EC55989_3543

Organism

Escherichia coli (strain 55989 / EAEC) [Complete proteome] [HAMAP]

Taxonomic identifier

585055 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	296 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Molecular function	Oxidoreductase EMBL CAU99722.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glyoxylate metabolic process Inferred from electronic annotation. Source: InterPro pentose-phosphate shunt Inferred from electronic annotation. Source: InterPro valine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-hydroxy-3-oxopropionate reductase activity Inferred from electronic annotation. Source: EC 3-hydroxyisobutyrate dehydrogenase activity Inferred from electronic annotation. Source: InterPro coenzyme binding Inferred from electronic annotation. Source: InterPro nucleotide binding Inferred from electronic annotation. Source: InterPro phosphogluconate dehydrogenase (decarboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7LH61 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: F5F6A782B0F7F0BE	FASTA	296	30,660
	10 20 30 40 50 60 MTMKVGFIGL GIMGKPMSKN LLKAGYSLVV ADRNPEAIAD VIAAGAETAS TAKAIAEQCD 70 80 90 100 110 120 VIITMLPNSP HVKEVALGEN GIIEGAKPGT VLIDMSSIAP LASREISEAL KAKGIDMLDA 130 140 150 160 170 180 PVSGGEPKAI DGTLSVMVGG DKAIFDKYYD LMKAMAGSVV HTGEIGAGNV TKLANQVIVA 190 200 210 220 230 240 LNIAAMSEAL TLATKAGVNP DLVYQAIRGG LAGSTVLDAK APMVMDRNFK PGFRIDLHIK 250 260 270 280 290 DLANALDTSH GVGAQLPLTA AVMEMMQALR ADGLGTADHS ALACYYEKLA KVEVTR

References

[1]

"Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths." Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P., Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H., Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E. , Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C., Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S., Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J., Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E. PLoS Genet. 5:E1000344-E1000344(2009) [PubMed: 19165319] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU928145 Genomic DNA. Translation: CAU99722.1.
RefSeq	YP_002404497.1. NC_011748.1.
3D structure databases
ProteinModelPortal	B7LH61.
SMR	B7LH61. Positions 3-296.
ModBase	Search...
Protein-protein interaction databases
STRING	B7LH61.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000128084; EBESCP00000120139; EBESCG00000126762.
GeneID	7146259.
GenomeReviews	Gene locus EC55989_3543 in contig CU928145_GR.
KEGG	eck:EC55989_3543.
PATRIC	38480622. VBIEscCol113220_3580.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000009837.
HOGENOM	HBG729179.
OMA	WSRRRES.
ProtClustDB	PRK11559.
Family and domain databases
InterPro	IPR002204. 3-OH-isobutyrate_DH-rel_CS. IPR015815. 3hydroxyacid_DH/Rdtase. IPR008927. 6-PGluconate_DH_C-like. IPR006115. 6PGDH_NADP-bd. IPR013328. DH_multihelical. IPR016040. NAD(P)-bd_dom. IPR006398. Tartro_sem_red. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. G3DSA:1.10.1040.10. Opine_DH. 1 hit.
KO	K00042.
PANTHER	PTHR22981. 3hydroxy_acid_DH. 1 hit.
Pfam	PF03446. NAD_binding_2. 1 hit. [Graphical view]
SUPFAM	SSF48179. 6DGDH_C_like. 1 hit.
TIGRFAMs	TIGR01505. Tartro_sem_red. 1 hit.
PROSITE	PS00895. 3_HYDROXYISOBUT_DH. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B7LH61_ECO55

Accession

Primary (citable) accession number: B7LH61

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)