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B7LGU9 (DADA_ECO55) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
D-amino acid dehydrogenase small subunit

EC=1.4.99.1
Gene names
Name:dadA
Ordered Locus Names:EC55989_1284
OrganismEscherichia coli (strain 55989 / EAEC) [Complete proteome] [HAMAP]
Taxonomic identifier585055 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length432 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Oxidative deamination of D-amino acids By similarity. HAMAP-Rule MF_01202

Catalytic activity

A D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor. HAMAP-Rule MF_01202

Cofactor

FAD By similarity. HAMAP-Rule MF_01202

Pathway

Amino-acid degradation; D-alanine degradation; NH(3) and pyruvate from D-alanine: step 1/1. HAMAP-Rule MF_01202

Subunit structure

Heterodimer of a small and a large subunit By similarity.

Sequence similarities

Belongs to the DadA oxidoreductase family.

Ontologies

Keywords
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processD-alanine catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionD-amino-acid dehydrogenase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 432432D-amino acid dehydrogenase small subunit HAMAP-Rule MF_01202
PRO_1000164640

Regions

Nucleotide binding3 – 1715FAD Potential

Sequences

Sequence LengthMass (Da)Tools
B7LGU9 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: EE747358845B6280

FASTA43247,607
        10         20         30         40         50         60 
MRVVILGSGV VGVASAWYLN QAGHEVTVID REPGAALETS AANAGQISPG YAAPWAAPGV 

        70         80         90        100        110        120 
PLKAIKWMFQ RHAPLAVRLD GTQFQLKWMW QMLRNCDTSH YMENKGRMVR LAEYSRDCLK 

       130        140        150        160        170        180 
ALRAETNIQY EGRQGGTLQL FRTEQQYENA TRDIAVLEDA GVPYQLLESS RLAEVEPALA 

       190        200        210        220        230        240 
EVAHKLTGGL QLPNDETGDC QLFTQNLARM AEQAGVKFRF NTPVDQLLCD GEQIYGVKCG 

       250        260        270        280        290        300 
DEVIKADAYV MAFGSYSTAM LKGIVDIPVY PLKGYSLTIP IAQEDGAPVS TILDETYKIA 

       310        320        330        340        350        360 
ITRFDNRIRV GGMAEIVGFN TELLQPRRET LEMVVRDLYP RGGHVEQATF WTGLRPMTPD 

       370        380        390        400        410        420 
GTPVVGRTRF KNLWLNTGHG TLGWTMACGS GQLLSDLLSG RTPAIPYEDL SVARYSRGFT 

       430 
PSRPGHLHGA HS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CU928145 Genomic DNA. Translation: CAU97143.1.
RefSeqYP_002402370.1. NC_011748.1.

3D structure databases

ProteinModelPortalB7LGU9.
SMRB7LGU9. Positions 1-68, 109-418.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING585055.EC55989_1284.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAU97143; CAU97143; EC55989_1284.
GeneID7148312.
KEGGeck:EC55989_1284.
PATRIC38476005. VBIEscCol113220_1314.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0665.
HOGENOMHOG000217450.
KOK00285.
OMALGHKVCV.
OrthoDBEOG6KMBD9.
ProtClustDBPRK00711.

Enzyme and pathway databases

BioCycECOL585055:GJOM-1309-MONOMER.
UniPathwayUPA00043; UER00498.

Family and domain databases

Gene3D3.40.50.720. 3 hits.
HAMAPMF_01202. DadA.
InterProIPR023080. D-aa_DH_ssu_DadA.
IPR006076. FAD-dep_OxRdtase.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF01266. DAO. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDADA_ECO55
AccessionPrimary (citable) accession number: B7LGU9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 10, 2009
Last modified: March 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways