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Protein

Trans-aconitate 2-methyltransferase

Gene

tam

Organism
Escherichia coli (strain 55989 / EAEC)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-3-(methoxycarbonyl)pent-2-enedioate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Names & Taxonomyi

Protein namesi
Recommended name:
Trans-aconitate 2-methyltransferaseUniRule annotation (EC:2.1.1.144UniRule annotation)
Gene namesi
Name:tamUniRule annotation
Ordered Locus Names:EC55989_1652
OrganismiEscherichia coli (strain 55989 / EAEC)
Taxonomic identifieri585055 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000746 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001966541 – 252Trans-aconitate 2-methyltransferaseAdd BLAST252

Structurei

3D structure databases

ProteinModelPortaliB7L7L9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the methyltransferase superfamily. Tam family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000125295.
KOiK00598.
OMAiETTYLHV.

Family and domain databases

Gene3Di1.10.150.290. 1 hit.
3.40.50.150. 1 hit.
HAMAPiMF_00560. Tran_acon_Me_trans. 1 hit.
InterProiIPR029063. SAM-dependent_MTases.
IPR023506. Trans-aconitate_MeTrfase.
IPR023149. Trans_acon_MeTrfase_C.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.

Sequencei

Sequence statusi: Complete.

B7L7L9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDWNPSLYL HFAAERSRPA VELLARVPLE NIEYVADLGC GPGNSTALLN
60 70 80 90 100
QRWPAARITG IDSSPAMIAE ARSALPDCQF VEADIRNWQP EQALDLIFAN
110 120 130 140 150
ASLQWLPDHY ELFPHLVSLL NPQGVLAVQM PDNWLEPTHV LMREVAWEQN
160 170 180 190 200
YPDRGRESLA GIHAYYDILS EAGCEVDIWR TTYYHQMPSH QAIIDWVTAT
210 220 230 240 250
GLRPWLQDLA ESEQQLFLTR YHQMLEEQYP LQENGQILLA FPRLFIVARR

TE
Length:252
Mass (Da):28,937
Last modified:February 10, 2009 - v1
Checksum:i8899F12D2B84BD58
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928145 Genomic DNA. Translation: CAU97505.1.
RefSeqiWP_001286556.1. NC_011748.1.

Genome annotation databases

EnsemblBacteriaiCAU97505; CAU97505; EC55989_1652.
KEGGieck:EC55989_1652.
PATRICi38476754. VBIEscCol113220_1684.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU928145 Genomic DNA. Translation: CAU97505.1.
RefSeqiWP_001286556.1. NC_011748.1.

3D structure databases

ProteinModelPortaliB7L7L9.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAU97505; CAU97505; EC55989_1652.
KEGGieck:EC55989_1652.
PATRICi38476754. VBIEscCol113220_1684.

Phylogenomic databases

HOGENOMiHOG000125295.
KOiK00598.
OMAiETTYLHV.

Family and domain databases

Gene3Di1.10.150.290. 1 hit.
3.40.50.150. 1 hit.
HAMAPiMF_00560. Tran_acon_Me_trans. 1 hit.
InterProiIPR029063. SAM-dependent_MTases.
IPR023506. Trans-aconitate_MeTrfase.
IPR023149. Trans_acon_MeTrfase_C.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTAM_ECO55
AccessioniPrimary (citable) accession number: B7L7L9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: February 10, 2009
Last modified: November 2, 2016
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.