B7L7D2 (ALLA_ECO55) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ureidoglycolate hydrolase
EC=3.5.3.19

Gene names

Name:	allA
Ordered Locus Names:	EC55989_0520

Organism

Escherichia coli (strain 55989 / EAEC) [Complete proteome] [HAMAP]

Taxonomic identifier

585055 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › Escherichia coli

Protein attributes

Sequence length	160 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the anaerobic utilization of allantoin. Reinforces the induction of genes involved in the degradation of allantoin and glyoxylate by producing glyoxylate By similarity. HAMAP-Rule MF_00616
Catalytic activity	(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2. HAMAP-Rule MF_00616
Pathway	Nitrogen metabolism; (S)-allantoin degradation; glyoxylate from (S)-ureidoglycolate: step 1/1. HAMAP-Rule MF_00616
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the ureidoglycolate hydrolase family.

Ontologies

Keywords
Biological process	Purine metabolism
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	allantoin catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway purine nucleobase catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	ureidoglycolate hydrolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 160	160	Ureidoglycolate hydrolase HAMAP-Rule MF_00616		PRO_1000147186

Sequences

	Sequence		Length	Mass (Da)
	B7L7D2 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: F891A4710EF92EC7	FASTA	160	18,249
	10 20 30 40 50 60 MKLQVLPLSQ EAFSAYGDVI ETQQRDFFHI NNGLVERYHD LALVEILEQD RTLISINRAQ 70 80 90 100 110 120 PANLPLTIYE LERHPLGTQA FIPMKGEVFV VVVALGDDKP DLSTLRAFIT NGEQGVNYHR 130 140 150 160 NVWHHPLFAW QRVTDFLTID RGGSDNCDVE SIPEQELCFA

References

[1]

"Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths." Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P., Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H., Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E. , Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C., Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S., Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J., Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E. PLoS Genet. 5:E1000344-E1000344(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 55989 / EAEC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU928145 Genomic DNA. Translation: CAU96393.1.
RefSeq	YP_002401636.1. NC_011748.1.
3D structure databases
ProteinModelPortal	B7L7D2.
SMR	B7L7D2. Positions 1-160.
ModBase	Search...
Protein-protein interaction databases
STRING	585055.EC55989_0520.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAU96393; CAU96393; EC55989_0520.
GeneID	7148122.
KEGG	eck:EC55989_0520.
PATRIC	38474398. VBIEscCol113220_0532.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3194.
HOGENOM	HOG000256169.
KO	K01483.
OMA	SQAFIPM.
ProtClustDB	PRK03606.
Enzyme and pathway databases
BioCyc	ECOL585055:GJOM-527-MONOMER.
UniPathway	UPA00395; UER00656.
Family and domain databases
Gene3D	2.60.120.480. 1 hit.
HAMAP	MF_00616. Ureidogly_hydro.
InterPro	IPR011051. RmlC_Cupin. IPR007247. Ureidogly_hydro. IPR023525. Ureidogly_hydro_bac. IPR024060. Ureidoglycolate_hydrolase_dom. [Graphical view]
PANTHER	PTHR21221. PTHR21221. 1 hit.
Pfam	PF04115. Ureidogly_hydro. 1 hit. [Graphical view]
PIRSF	PIRSF017306. Ureidogly_hydro. 1 hit.
SUPFAM	SSF51182. RmlC_like_cupin. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALLA_ECO55

Accession

Primary (citable) accession number: B7L7D2

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	February 10, 2009
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program