Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Precorrin-2 C20-methyltransferase

Gene

Mchl_5690

Organism
Methylobacterium extorquens (strain CM4 / NCIMB 13688) (Methylobacterium chloromethanicum)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. precorrin-2 C20-methyltransferase activity Source: InterPro
  2. precorrin-2 dehydrogenase activity Source: InterPro

GO - Biological processi

  1. cobalamin biosynthetic process Source: InterPro
  2. porphyrin-containing compound biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Enzyme and pathway databases

BioCyciMCHL440085:GCXT-5770-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Precorrin-2 C20-methyltransferaseImported
Gene namesi
Ordered Locus Names:Mchl_5690Imported
Encoded oniPlasmid pCMU01Imported
OrganismiMethylobacterium extorquens (strain CM4 / NCIMB 13688) (Methylobacterium chloromethanicum)Imported
Taxonomic identifieri440085 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
ProteomesiUP000002385: Plasmid pCMU01

Interactioni

Protein-protein interaction databases

STRINGi440085.Mchl_5690.

Structurei

3D structure databases

ProteinModelPortaliB7L3K2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the precorrin methyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2243.
HOGENOMiHOG000291191.
KOiK03394.
OMAiMRERSGV.
OrthoDBiEOG647TWW.

Family and domain databases

Gene3Di3.40.1010.10. 1 hit.
InterProiIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR012382. Cbl_synth_CobI/CbiL.
IPR006364. Cbl_synth_CobI/CbiL_core.
IPR003043. Uropor_MeTrfase_CS.
[Graphical view]
PfamiPF00590. TP_methylase. 1 hit.
[Graphical view]
PIRSFiPIRSF036427. Precrrn-2_mtase. 1 hit.
SUPFAMiSSF53790. SSF53790. 1 hit.
TIGRFAMsiTIGR01467. cobI_cbiL. 1 hit.
PROSITEiPS00840. SUMT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7L3K2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEAVAGEPTV LATVSTGTLY GVGMGPGDPE YLTLKALRVL ERAPILVHFC
60 70 80 90 100
KKGRRGNART IADAVVCDPA RECPLVYPYT IELPPGHGDY VAALAAFYDD
110 120 130 140 150
AAGRLADHLG AGRDVAILSE GDPFFYGSFM HLWRRLKDRF PVEVVPGVTG
160 170 180 190 200
MSGCWTRAGT PITWGDDVLT VLPATLPHAA LAERLRGTDA AVVMKLGRHL
210 220 230 240 250
PKVRAALSEA GLLDRAVYVE RGTMAGEKVI PLAGKPDDEA PYFSMVLVPG

EGRRP
Length:255
Mass (Da):27,305
Last modified:February 10, 2009 - v1
Checksum:i50940A136EC53EC4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001299 Genomic DNA. Translation: ACK86410.1.
RefSeqiWP_012606300.1. NC_011758.1.
YP_002424338.1. NC_011758.1.

Genome annotation databases

EnsemblBacteriaiACK86410; ACK86410; Mchl_5690.
GeneIDi7119039.
KEGGimch:Mchl_5690.
PATRICi22505629. VBIMetChl132133_5621.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001299 Genomic DNA. Translation: ACK86410.1.
RefSeqiWP_012606300.1. NC_011758.1.
YP_002424338.1. NC_011758.1.

3D structure databases

ProteinModelPortaliB7L3K2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi440085.Mchl_5690.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACK86410; ACK86410; Mchl_5690.
GeneIDi7119039.
KEGGimch:Mchl_5690.
PATRICi22505629. VBIMetChl132133_5621.

Phylogenomic databases

eggNOGiCOG2243.
HOGENOMiHOG000291191.
KOiK03394.
OMAiMRERSGV.
OrthoDBiEOG647TWW.

Enzyme and pathway databases

BioCyciMCHL440085:GCXT-5770-MONOMER.

Family and domain databases

Gene3Di3.40.1010.10. 1 hit.
InterProiIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR012382. Cbl_synth_CobI/CbiL.
IPR006364. Cbl_synth_CobI/CbiL_core.
IPR003043. Uropor_MeTrfase_CS.
[Graphical view]
PfamiPF00590. TP_methylase. 1 hit.
[Graphical view]
PIRSFiPIRSF036427. Precrrn-2_mtase. 1 hit.
SUPFAMiSSF53790. SSF53790. 1 hit.
TIGRFAMsiTIGR01467. cobI_cbiL. 1 hit.
PROSITEiPS00840. SUMT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of plasmid1 of Methylobacterium chloromethanicum CM4."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Marx C., Richardson P.
    Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CM4 / NCIMB 13688Imported.

Entry informationi

Entry nameiB7L3K2_METC4
AccessioniPrimary (citable) accession number: B7L3K2
Entry historyi
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: January 7, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported, PlasmidImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.