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B7KV98

- IF3_METC4

UniProt

B7KV98 - IF3_METC4

Protein

Translation initiation factor IF-3

Gene

infC

Organism
Methylobacterium extorquens (strain CM4 / NCIMB 13688) (Methylobacterium chloromethanicum)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 35 (01 Oct 2014)
      Sequence version 1 (10 Feb 2009)
      Previous versions | rss
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    Functioni

    IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.UniRule annotation

    GO - Molecular functioni

    1. translation initiation factor activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis

    Enzyme and pathway databases

    BioCyciMCHL440085:GCXT-1952-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Translation initiation factor IF-3UniRule annotation
    Gene namesi
    Name:infCUniRule annotation
    Ordered Locus Names:Mchl_1906
    OrganismiMethylobacterium extorquens (strain CM4 / NCIMB 13688) (Methylobacterium chloromethanicum)
    Taxonomic identifieri440085 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
    ProteomesiUP000002385: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 173173Translation initiation factor IF-3PRO_1000202541Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi440085.Mchl_1906.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the IF-3 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0290.
    HOGENOMiHOG000035157.
    KOiK02520.
    OMAiPRYNEFI.
    OrthoDBiEOG63JRGJ.

    Family and domain databases

    Gene3Di3.10.20.80. 1 hit.
    3.30.110.10. 1 hit.
    HAMAPiMF_00080. IF_3.
    InterProiIPR001288. Translation_initiation_fac_3.
    IPR019815. Translation_initiation_fac_3_C.
    IPR019814. Translation_initiation_fac_3_N.
    [Graphical view]
    PANTHERiPTHR10938. PTHR10938. 1 hit.
    PfamiPF00707. IF3_C. 1 hit.
    PF05198. IF3_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF54364. SSF54364. 1 hit.
    SSF55200. SSF55200. 1 hit.
    TIGRFAMsiTIGR00168. infC. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B7KV98-1 [UniParc]FASTAAdd to Basket

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    MPAPQKDGPR ANRDIRGVRD VQLIDQDGQN RGVVPFFDAL AMAEEVGLDL    50
    VEIAPNSVPP VCKFLDYGRF RFNEQKKQNE ARKRQKTVEV KEIKLRPGID 100
    KHDYEVKMKA VQRFFEEGDK VKVTLRFRGR EIAHQDIGLR LLERVKQETQ 150
    EIAKVESEPM LEGRQMIMIL APR 173
    Length:173
    Mass (Da):20,038
    Last modified:February 10, 2009 - v1
    Checksum:i53E792654A2AD706
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001298 Genomic DNA. Translation: ACK82769.1.
    RefSeqiYP_002420697.1. NC_011757.1.

    Genome annotation databases

    EnsemblBacteriaiACK82769; ACK82769; Mchl_1906.
    GeneIDi7116721.
    KEGGimch:Mchl_1906.
    PATRICi22498006. VBIMetChl132133_1842.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001298 Genomic DNA. Translation: ACK82769.1 .
    RefSeqi YP_002420697.1. NC_011757.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 440085.Mchl_1906.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACK82769 ; ACK82769 ; Mchl_1906 .
    GeneIDi 7116721.
    KEGGi mch:Mchl_1906.
    PATRICi 22498006. VBIMetChl132133_1842.

    Phylogenomic databases

    eggNOGi COG0290.
    HOGENOMi HOG000035157.
    KOi K02520.
    OMAi PRYNEFI.
    OrthoDBi EOG63JRGJ.

    Enzyme and pathway databases

    BioCyci MCHL440085:GCXT-1952-MONOMER.

    Family and domain databases

    Gene3Di 3.10.20.80. 1 hit.
    3.30.110.10. 1 hit.
    HAMAPi MF_00080. IF_3.
    InterProi IPR001288. Translation_initiation_fac_3.
    IPR019815. Translation_initiation_fac_3_C.
    IPR019814. Translation_initiation_fac_3_N.
    [Graphical view ]
    PANTHERi PTHR10938. PTHR10938. 1 hit.
    Pfami PF00707. IF3_C. 1 hit.
    PF05198. IF3_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54364. SSF54364. 1 hit.
    SSF55200. SSF55200. 1 hit.
    TIGRFAMsi TIGR00168. infC. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Methylobacterium chloromethanicum CM4."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Marx C., Richardson P.
      Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CM4 / NCIMB 13688.

    Entry informationi

    Entry nameiIF3_METC4
    AccessioniPrimary (citable) accession number: B7KV98
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 22, 2009
    Last sequence update: February 10, 2009
    Last modified: October 1, 2014
    This is version 35 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. Translation initiation factors
      List of translation initiation factor entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3