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B7KV98 (IF3_METC4) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Translation initiation factor IF-3
Gene names
Name:infC
Ordered Locus Names:Mchl_1906
OrganismMethylobacterium extorquens (strain CM4 / NCIMB 13688) (Methylobacterium chloromethanicum) [Complete proteome] [HAMAP]
Taxonomic identifier440085 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium

Protein attributes

Sequence length173 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins By similarity. HAMAP-Rule MF_00080

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00080

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00080.

Sequence similarities

Belongs to the IF-3 family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   Molecular functionInitiation factor
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 173173Translation initiation factor IF-3 HAMAP-Rule MF_00080
PRO_1000202541

Sequences

Sequence LengthMass (Da)Tools
B7KV98 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: 53E792654A2AD706

FASTA17320,038
        10         20         30         40         50         60 
MPAPQKDGPR ANRDIRGVRD VQLIDQDGQN RGVVPFFDAL AMAEEVGLDL VEIAPNSVPP 

        70         80         90        100        110        120 
VCKFLDYGRF RFNEQKKQNE ARKRQKTVEV KEIKLRPGID KHDYEVKMKA VQRFFEEGDK 

       130        140        150        160        170 
VKVTLRFRGR EIAHQDIGLR LLERVKQETQ EIAKVESEPM LEGRQMIMIL APR 

« Hide

References

[1]"Complete sequence of chromosome of Methylobacterium chloromethanicum CM4."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Marx C., Richardson P.
Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CM4 / NCIMB 13688.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001298 Genomic DNA. Translation: ACK82769.1.
RefSeqYP_002420697.1. NC_011757.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING440085.Mchl_1906.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACK82769; ACK82769; Mchl_1906.
GeneID7116721.
KEGGmch:Mchl_1906.
PATRIC22498006. VBIMetChl132133_1842.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0290.
HOGENOMHOG000035157.
KOK02520.
OMAPRYNEFI.
OrthoDBEOG63JRGJ.

Enzyme and pathway databases

BioCycMCHL440085:GCXT-1952-MONOMER.

Family and domain databases

Gene3D3.10.20.80. 1 hit.
3.30.110.10. 1 hit.
HAMAPMF_00080. IF_3.
InterProIPR001288. Translation_initiation_fac_3.
IPR019815. Translation_initiation_fac_3_C.
IPR019814. Translation_initiation_fac_3_N.
[Graphical view]
PANTHERPTHR10938. PTHR10938. 1 hit.
PfamPF00707. IF3_C. 1 hit.
PF05198. IF3_N. 1 hit.
[Graphical view]
SUPFAMSSF54364. SSF54364. 1 hit.
SSF55200. SSF55200. 1 hit.
TIGRFAMsTIGR00168. infC. 1 hit.
ProtoNetSearch...

Entry information

Entry nameIF3_METC4
AccessionPrimary (citable) accession number: B7KV98
Entry history
Integrated into UniProtKB/Swiss-Prot: September 22, 2009
Last sequence update: February 10, 2009
Last modified: May 14, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries