B7KV98 (IF3_METC4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Translation initiation factor IF-3

Gene names

Name:	infC
Ordered Locus Names:	Mchl_1906

Organism

Methylobacterium extorquens (strain CM4 / NCIMB 13688) (Methylobacterium chloromethanicum) [Complete proteome] [HAMAP]

Taxonomic identifier

440085 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium › Methylobacterium extorquens group › Methylobacterium extorquens

Protein attributes

Sequence length	173 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins By similarity. HAMAP-Rule MF_00080
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the IF-3 family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Molecular function	Initiation factor
Technical term	Complete proteome
Gene Ontology (GO)
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	translation initiation factor activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 173	173	Translation initiation factor IF-3 HAMAP-Rule MF_00080		PRO_1000202541

Sequences

	Sequence		Length	Mass (Da)
	B7KV98 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 53E792654A2AD706	FASTA	173	20,038
	10 20 30 40 50 60 MPAPQKDGPR ANRDIRGVRD VQLIDQDGQN RGVVPFFDAL AMAEEVGLDL VEIAPNSVPP 70 80 90 100 110 120 VCKFLDYGRF RFNEQKKQNE ARKRQKTVEV KEIKLRPGID KHDYEVKMKA VQRFFEEGDK 130 140 150 160 170 VKVTLRFRGR EIAHQDIGLR LLERVKQETQ EIAKVESEPM LEGRQMIMIL APR

References

[1]

"Complete sequence of chromosome of Methylobacterium chloromethanicum CM4." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Marx C., Richardson P. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CM4 / NCIMB 13688.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001298 Genomic DNA. Translation: ACK82769.1.
RefSeq	YP_002420697.1. NC_011757.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	440085.Mchl_1906.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACK82769; ACK82769; Mchl_1906.
GeneID	7116721.
KEGG	mch:Mchl_1906.
PATRIC	22498006. VBIMetChl132133_1842.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0290.
HOGENOM	HOG000035157.
KO	K02520.
OMA	APKAPIN.
ProtClustDB	PRK00028.
Family and domain databases
Gene3D	3.10.20.80. 1 hit.
HAMAP	MF_00080. IF-3.
InterPro	IPR001288. Translation_initiation_fac_3. IPR019815. Translation_initiation_fac_3_C. IPR019814. Translation_initiation_fac_3_N. [Graphical view]
PANTHER	PTHR10938. PTHR10938. 1 hit.
Pfam	PF00707. IF3_C. 1 hit. PF05198. IF3_N. 1 hit. [Graphical view]
SUPFAM	SSF54364. IF3. 1 hit. SSF55200. IF3. 1 hit.
TIGRFAMs	TIGR00168. infC. 1 hit.
PROSITE	PS00938. IF3. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

IF3_METC4

Accession

Primary (citable) accession number: B7KV98

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 22, 2009
Last sequence update:	February 10, 2009
Last modified:	May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program