B7KV55 (RSMG_METC4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribosomal RNA small subunit methyltransferase G
EC=2.1.1.170

Alternative name(s):
16S rRNA 7-methylguanosine methyltransferase
Short name=16S rRNA m7G methyltransferase

Gene names

Name:	rsmG
Ordered Locus Names:	Mchl_1863

Organism

Methylobacterium chloromethanicum (strain CM4 / NCIMB 13688) [Complete proteome] [HAMAP]

Taxonomic identifier

440085 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	211 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Specifically methylates the N7 position of guanosine in position 527 of 16S rRNA By similarity. HAMAP MF_00074
Catalytic activity	S-adenosyl-L-methionine + guanosine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanosine(527) in 16S rRNA. HAMAP MF_00074
Subcellular location	Cytoplasm Potential HAMAP MF_00074.
Sequence similarities	Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.

Ontologies

Keywords
Biological process	rRNA processing
Cellular component	Cytoplasm
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	rRNA methyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 211	211	Ribosomal RNA small subunit methyltransferase G HAMAP MF_00074		PRO_1000118193

Sequences

	Sequence		Length	Mass (Da)
	B7KV55 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 3197D7A65593DE70	FASTA	211	23,019
	10 20 30 40 50 60 MSTDLRTRVL SEHHVSRETA ASLDLYVAQL TRWQTVKNLV GPATLKEVWH RHIADALQLL 70 80 90 100 110 120 SIAPEATRWL DLGSGAGIPG LILALAGKER PGFHVRLVES NARKCAFLSE TARLTGAPVT 130 140 150 160 170 180 VHNARIEAVI GTLTDTEIVC ARALAPLSQL LAWTEPLLTS GTTGLFPKGR DAATELTEAE 190 200 210 DEWTFTRDLI PSRTDSQARI VRVTSLSRVD P

References

[1]

"Complete sequence of chromosome of Methylobacterium chloromethanicum CM4." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Marx C., Richardson P. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CM4 / NCIMB 13688.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001298 Genomic DNA. Translation: ACK82726.1.
RefSeq	YP_002420654.1. NC_011757.1.
3D structure databases
ProteinModelPortal	B7KV55.
ModBase	Search...
Protein-protein interaction databases
STRING	B7KV55.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7113591.
GenomeReviews	Gene locus Mchl_1863 in contig CP001298_GR.
KEGG	mch:Mchl_1863.
PATRIC	22497908. VBIMetChl132133_1793.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG686577.
OMA	GGQGWIV.
ProtClustDB	CLSK2330754.
Family and domain databases
HAMAP	MF_00074. 16SrRNA_methyltr_G. [Tree]
InterPro	IPR003682. rRNA_ssu_MeTfrase_G. [Graphical view]
KO	K03501.
Pfam	PF02527. GidB. 1 hit. [Graphical view]
PIRSF	PIRSF003078. GidB. 1 hit.
TIGRFAMs	TIGR00138. GidB. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RSMG_METC4

Accession

Primary (citable) accession number: B7KV55

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	February 10, 2009
Last modified:	January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program