ID   B7KRT0_METC4            Unreviewed;       461 AA.
AC   B7KRT0;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   SubName: Full=Metal dependent phosphohydrolase {ECO:0000313|EMBL:ACK82292.1};
GN   OrderedLocusNames=Mchl_1412 {ECO:0000313|EMBL:ACK82292.1};
OS   Methylorubrum extorquens (strain CM4 / NCIMB 13688) (Methylobacterium
OS   extorquens).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylobacteriaceae; Methylorubrum.
OX   NCBI_TaxID=440085 {ECO:0000313|EMBL:ACK82292.1, ECO:0000313|Proteomes:UP000002385};
RN   [1] {ECO:0000313|Proteomes:UP000002385}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CM4 / NCIMB 13688 {ECO:0000313|Proteomes:UP000002385};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N.,
RA   Marx C., Richardson P.;
RT   "Complete sequence of chromosome of Methylobacterium chloromethanicum
RT   CM4.";
RL   Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ACK82292.1, ECO:0000313|Proteomes:UP000002385}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CM4 / NCIMB 13688 {ECO:0000313|Proteomes:UP000002385};
RX   PubMed=22887658; DOI=10.1128/JB.01009-12;
RA   Marx C.J., Bringel F., Chistoserdova L., Moulin L., Farhan Ul Haque M.,
RA   Fleischman D.E., Gruffaz C., Jourand P., Knief C., Lee M.C., Muller E.E.,
RA   Nadalig T., Peyraud R., Roselli S., Russ L., Goodwin L.A., Ivanova N.,
RA   Kyrpides N., Lajus A., Land M.L., Medigue C., Mikhailova N., Nolan M.,
RA   Woyke T., Stolyar S., Vorholt J.A., Vuilleumier S.;
RT   "Complete genome sequences of six strains of the genus Methylobacterium.";
RL   J. Bacteriol. 194:4746-4748(2012).
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DR   EMBL; CP001298; ACK82292.1; -; Genomic_DNA.
DR   RefSeq; WP_015950165.1; NC_011757.1.
DR   AlphaFoldDB; B7KRT0; -.
DR   KEGG; mch:Mchl_1412; -.
DR   HOGENOM; CLU_040286_1_0_5; -.
DR   Proteomes; UP000002385; Chromosome.
DR   GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:UniProt.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 2.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR   PANTHER; PTHR45228:SF4; LIPOPROTEIN-RELATED; 1.
DR   Pfam; PF13487; HD_5; 2.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 2.
DR   PROSITE; PS51832; HD_GYP; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ACK82292.1}.
FT   DOMAIN          264..459
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
SQ   SEQUENCE   461 AA;  49925 MW;  FA1EACAD7B79CD25 CRC64;
     MHIVSGSEGE QTVQLSEILG ALSHALDLTE GQPVGHCVRA TWIGFHIGRQ IGLPELQLWE
     LYHTVMLKDL GCSSNAARIC ELYLSDDLSF KRDFKTVSDS LPKVLGFVFS HTGLKAGLAD
     RFRAVLNILQ NGGTIVDELI QTRCQRGAEI ARQLRFPASV CEAIHALDEH WNGGGRPDRL
     AGPAIPLYAR VALLAQVVDV FHASAGRAAA LAEVRARAGT WFDPQIVACF EAAAAAPGFW
     ETLASDGVEA AVFALAPRSP IVVDEDYLDD IARAFAQIID AKSPFTSGHS ERVAVYADMV
     AAELGYTPER RRWLKRAALL HDVGKLGVSN AILDKNGKLD EAEWEDMRNH ASMSETILTR
     VAAFHEIARI GGGHHERLDG RGYPRGLKGE AIAPETRIVS VADVFDALTA DRPYRKAMPV
     EKALAIMRGD VGTAFDPDCF AALERAIAGL DTELAPAHEA A
//