B7KRB0 (B7KRB0_METC4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2-dehydro-3-deoxyphosphooctonate aldolase HAMAP MF_00056
EC=2.5.1.55 HAMAP MF_00056

Alternative name(s):
3-deoxy-D-manno-octulosonic acid 8-phosphate synthase HAMAP MF_00056
KDO-8-phosphate synthase HAMAP MF_00056
Phospho-2-dehydro-3-deoxyoctonate aldolase HAMAP MF_00056

Gene names

Name:	kdsA HAMAP MF_00056
Ordered Locus Names:	Mchl_3008

Organism

Methylobacterium chloromethanicum (strain CM4 / NCIMB 13688) [Complete proteome] [HAMAP] EMBL ACK83846.1

Taxonomic identifier

440085 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	282 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Phosphoenolpyruvate + D-arabinose 5-phosphate + H2O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate. HAMAP MF_00056
Pathway	Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis. HAMAP MF_00056 Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3. HAMAP MF_00056
Subcellular location	Cytoplasm By similarity HAMAP MF_00056.
Sequence similarities	Belongs to the KdsA family. HAMAP MF_00056

Ontologies

Keywords
Biological process	Lipopolysaccharide biosynthesis HAMAP MF_00056
Cellular component	Cytoplasm HAMAP MF_00056
Molecular function	Transferase HAMAP MF_00056
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	3-deoxy-8-phosphooctulonate synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7KRB0 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: F64900998AE72F53	FASTA	282	29,245
	10 20 30 40 50 60 MPETAQTSGS VVQTGGVAFA NHLPLALIAG PCQLEGRNHA LEIAAALKEM AAKLGIGLVF 70 80 90 100 110 120 KSSFDKANRT SGRTARGVGL DEALPVFAEI RESLGLPVLT DVHEAEHCAR AAQAVDILQI 130 140 150 160 170 180 PAFLCRQTDL LLAAAATGRA VNVKKGQFLA PWDMAHVAAK VTEAGNPNVI VTERGASFGY 190 200 210 220 230 240 NTLVSDMRSL PIMARVTGGA PVVFDATHSV QQPGGQGTTS GGQREFVAVL ARAAVAVGVA 250 260 270 280 GVFIETHPDP DRAPSDGPNM VALADLPALI ETLMAFDRLA KA

References

[1]

"Complete sequence of chromosome of Methylobacterium chloromethanicum CM4." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Marx C., Richardson P. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CM4 / NCIMB 13688.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001298 Genomic DNA. Translation: ACK83846.1.
RefSeq	YP_002421774.1. NC_011757.1.
3D structure databases
ProteinModelPortal	B7KRB0.
ModBase	Search...
Protein-protein interaction databases
STRING	B7KRB0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7118205.
GenomeReviews	Gene locus Mchl_3008 in contig CP001298_GR.
KEGG	mch:Mchl_3008.
PATRIC	22500306. VBIMetChl132133_2978.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG575990.
OMA	ESRDHAF.
ProtClustDB	PRK05198.
Family and domain databases
HAMAP	MF_00056. KDO8P_synth. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR006218. DAHP1/KDSA. IPR006269. KDO8P_synthase. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01627.
PANTHER	PTHR21057:SF2. KDO8P_synthase. 1 hit.
Pfam	PF00793. DAHP_synth_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR01362. KDO8P_synth. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B7KRB0_METC4

Accession

Primary (citable) accession number: B7KRB0

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	January 25, 2012
This is version 19 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)