B7KPS0 (B7KPS0_METC4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Homoserine kinase HAMAP MF_00301
Short name=HK HAMAP MF_00301
Short name=HSK HAMAP MF_00301
EC=2.7.1.39 HAMAP MF_00301

Gene names

Name:	thrB HAMAP MF_00301
Ordered Locus Names:	Mchl_2817

Organism

Methylobacterium chloromethanicum (strain CM4 / NCIMB 13688) [Complete proteome] [HAMAP] EMBL ACK83656.1

Taxonomic identifier

440085 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	329 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + L-homoserine = ADP + O-phospho-L-homoserine. HAMAP MF_00301 SAAS SAAS002575
Pathway	Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5. HAMAP MF_00301 SAAS SAAS002575
Sequence similarities	Belongs to the pseudomonas-type thrB family. HAMAP MF_00301

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Threonine biosynthesis HAMAP MF_00301 SAAS SAAS002575
Ligand	ATP-binding HAMAP MF_00301 SAAS SAAS002575 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00301 SAAS SAAS002575 EMBL ACK83656.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	threonine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW homoserine kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7KPS0 [UniParc]. Last modified February 10, 2009. Version 1. Checksum: 6540F2A6195C71B3	FASTA	329	35,794
	10 20 30 40 50 60 MRETGSGTVA VYTDVSDEAL RAFLREYELG DLLSYKGIAE GVENSNFFLH TSTGNYILTL 70 80 90 100 110 120 YEKRVNAADL PFFINLMGHL ARAGLACPQP VRNRAGTALG HLCGRPAAIV TFLEGVSLSR 130 140 150 160 170 180 PNADHCRALG AALAGLHAAG RDFPMVRANN LSVEAWRPLF VQAEAQADTV APGLAARTRA 190 200 210 220 230 240 DLDWLEASWP QGLPAGVIHA DLFTDNVFFI GDAVSGLIDF YFACTDAFAY DLAISLNAWC 250 260 270 280 290 300 FDADGTFHRD KAGAMIAGYD AVRALEPAEI AALPILARGA AMRFMLTRLV DWLNVPPGAL 310 320 VQPKDPLEYD RRLAFHRTAT DARDYGWEK

References

[1]

"Complete sequence of chromosome of Methylobacterium chloromethanicum CM4." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Marx C., Richardson P. Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CM4 / NCIMB 13688.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001298 Genomic DNA. Translation: ACK83656.1.
RefSeq	YP_002421584.1. NC_011757.1.
3D structure databases
ProteinModelPortal	B7KPS0.
ModBase	Search...
Protein-protein interaction databases
STRING	B7KPS0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7115046.
GenomeReviews	Gene locus Mchl_2817 in contig CP001298_GR.
KEGG	mch:Mchl_2817.
PATRIC	22499907. VBIMetChl132133_2783.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG309377.
OMA	ICLNAWC.
ProtClustDB	CLSK2331237.
Family and domain databases
HAMAP	MF_00301. Homoser_kinase_2. [Tree]
InterPro	IPR002575. Aminoglycoside_PTrfase. IPR005280. Homoserine_kinase_ThrB. IPR011009. Kinase-like_dom. [Graphical view]
KO	K02204.
Pfam	PF01636. APH. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
TIGRFAMs	TIGR00938. ThrB_alt. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B7KPS0_METC4

Accession

Primary (citable) accession number: B7KPS0

Entry history

Integrated into UniProtKB/TrEMBL:	February 10, 2009
Last sequence update:	February 10, 2009
Last modified:	December 14, 2011
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)