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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Cyanothece sp. (strain PCC 7424) (Synechococcus sp. (strain ATCC 29155))
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei349 – 3491UniRule annotation
Active sitei453 – 4531UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCSP65393:GJP7-3822-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:PCC7424_3777
OrganismiCyanothece sp. (strain PCC 7424) (Synechococcus sp. (strain ATCC 29155))
Taxonomic identifieri65393 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesCyanothece
ProteomesiUP000002384 Componenti: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 526526Glucose-6-phosphate isomerasePRO_1000125714Add
BLAST

Proteomic databases

PRIDEiB7KJ74.

Interactioni

Protein-protein interaction databases

STRINGi65393.PCC7424_3777.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000131425.
KOiK01810.
OMAiRQVGHYW.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7KJ74-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEYQTLWQRY LDWLYYHQNL GFYVDISRIR FDDAFIDSIK PKFEKAFKDM
60 70 80 90 100
EELEKGAIAN PDEGRMVGHY WLRAPELAPN DEVRKEITEP LKQIEEFVAK
110 120 130 140 150
VLKGTIKPPT ADKFTDIISV GIGGSALGPQ FVSEALAGDF PPMGIHFIDN
160 170 180 190 200
TDPAGIDRVV TRLKDRLKST LVIVTSKSGG TPETRNGMLE MRHAYEKNGL
210 220 230 240 250
DFPKYAVAVT MPGSKMDQVA HDWLARFPMQ DWVGGRTSEL SAVGLLPAAL
260 270 280 290 300
QGIDIQGMLA GAKEMDEATR VKDLKNNPSA LLALSWYYAG NGKGEKDMVV
310 320 330 340 350
LPYKDSLALL SRYLQQLVME SLGKEKDLDG NTVYQGIAVY GNKGSTDQHA
360 370 380 390 400
YVQQLREGVP NFFVTFIEVL EDRQGSSIEL EPGVTSGDYL AGFIQGTRQA
410 420 430 440 450
LYENHRDSIT ITIPEVNPRT VGALVALYER AVSFYGSLVN VNAYHQPGVE
460 470 480 490 500
AGKKAAASIL ELQQNVMKAL KEAGTELDLE TLSQKAGHPD KVEAVYKIVR
510 520
HLAANNRGVM LKGDLGKPTT LKVSFG
Length:526
Mass (Da):58,182
Last modified:February 9, 2009 - v1
Checksum:iBF32CB0EDB19E7A5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001291 Genomic DNA. Translation: ACK72158.1.
RefSeqiWP_015955750.1. NC_011729.1.
YP_002379026.1. NC_011729.1.

Genome annotation databases

EnsemblBacteriaiACK72158; ACK72158; PCC7424_3777.
KEGGicyc:PCC7424_3777.
PATRICi21556544. VBICyaSp136448_3873.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001291 Genomic DNA. Translation: ACK72158.1.
RefSeqiWP_015955750.1. NC_011729.1.
YP_002379026.1. NC_011729.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi65393.PCC7424_3777.

Proteomic databases

PRIDEiB7KJ74.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACK72158; ACK72158; PCC7424_3777.
KEGGicyc:PCC7424_3777.
PATRICi21556544. VBICyaSp136448_3873.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000131425.
KOiK01810.
OMAiRQVGHYW.
OrthoDBiEOG64R61J.

Enzyme and pathway databases

UniPathwayiUPA00109; UER00181.
UPA00138.
BioCyciCSP65393:GJP7-3822-MONOMER.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Novel metabolic attributes of the genus Cyanothece, comprising a group of unicellular nitrogen-fixing Cyanobacteria."
    Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H., Sherman L.A., Pakrasi H.B.
    MBio 2:E214-E214(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 7424.

Entry informationi

Entry nameiG6PI_CYAP7
AccessioniPrimary (citable) accession number: B7KJ74
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2009
Last sequence update: February 9, 2009
Last modified: March 31, 2015
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.