ID   B7KIE1_GLOC7            Unreviewed;       348 AA.
AC   B7KIE1;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 77.
DE   SubName: Full=Response regulator receiver modulated metal dependent phosphohydrolase {ECO:0000313|EMBL:ACK73628.1};
GN   OrderedLocusNames=PCC7424_5280 {ECO:0000313|EMBL:ACK73628.1};
OS   Gloeothece citriformis (strain PCC 7424) (Cyanothece sp. (strain PCC
OS   7424)).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Aphanothecaceae; Gloeothece; Gloeothece citriformis.
OX   NCBI_TaxID=65393 {ECO:0000313|EMBL:ACK73628.1, ECO:0000313|Proteomes:UP000002384};
RN   [1] {ECO:0000313|Proteomes:UP000002384}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7424 {ECO:0000313|Proteomes:UP000002384};
RX   PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
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DR   EMBL; CP001291; ACK73628.1; -; Genomic_DNA.
DR   RefSeq; WP_015957206.1; NC_011729.1.
DR   AlphaFoldDB; B7KIE1; -.
DR   STRING; 65393.PCC7424_5280; -.
DR   KEGG; cyc:PCC7424_5280; -.
DR   eggNOG; COG3437; Bacteria.
DR   HOGENOM; CLU_000445_92_10_3; -.
DR   OrthoDB; 9804747at2; -.
DR   Proteomes; UP000002384; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR037522; HD_GYP_dom.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   PANTHER; PTHR45228:SF1; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186; 1.
DR   PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR   Pfam; PF13487; HD_5; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR   PROSITE; PS51832; HD_GYP; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ACK73628.1};
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002384}.
FT   DOMAIN          31..147
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          155..348
FT                   /note="HD-GYP"
FT                   /evidence="ECO:0000259|PROSITE:PS51832"
FT   MOD_RES         80
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   348 AA;  39748 MW;  8536C32448DFF631 CRC64;
     MKVSHILLKT VSGNPINISA MNAIVNCEPA KILIIDEHPH SRMAVKDLLC LDGYEVIETD
     ENLNITDHVL KKRPDLILLD VMMPQMEGFK VCQQLKQDER TSGIPIIFMT VAEDHQLRRR
     CTQAGGDDVL TKPIERLKLS SRVKSLIEQK RLYEGLDQIE QVLFAIARAI ENRYPNNGNS
     CARLATLANS FGKYLQLPFS SLQNLRYAAY LHDIGMVSIP DEIMLKKGEL TPEERGIIQQ
     HVLIGEEICQ PLPNRRGVLP IIRHHHERWD GTGYPDGLVG NEIPWLAQIF QILDIYVALI
     SERPHKKIYH PQEAIEIITE EGAKGWRNPE LVKQFTNFII TRELLIHN
//