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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Cyanothece sp. (strain PCC 7424) (Synechococcus sp. (strain ATCC 29155))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei191GTPUniRule annotation1
Binding sitei195GTPUniRule annotation1
Binding sitei239GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi73 – 77GTPUniRule annotation5
Nucleotide bindingi160 – 162GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:PCC7424_5023Imported
OrganismiCyanothece sp. (strain PCC 7424) (Synechococcus sp. (strain ATCC 29155))Imported
Taxonomic identifieri65393 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesCyanothecaceaeCyanothece
Proteomesi
  • UP000002384 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi65393.PCC7424_5023.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini65 – 257TubulinInterPro annotationAdd BLAST193
Domaini259 – 376Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiMRAVKGI.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR037103. Tubulin/FtsZ_C_sf.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B7KFQ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTHNDEIRLT YSSVNSTEYA DPSANEESYH SLNSAGIPFH RNNEPQVNPR
60 70 80 90 100
ERARSNTIVQ SNVAQIKVIG VGGGGCNAVN RMIASGIIGI EFWSINTDAQ
110 120 130 140 150
ALAHSAAPQR LQIGQKITRG LGAGGNPAIG QKAAEESRDE IAHALENTDL
160 170 180 190 200
VFITAGMGGG TGTGAAPIVA EVAKEMGCLT VGVVTRPFTF EGRRRTNQAE
210 220 230 240 250
EGINALQSRV DTLIVIPNNQ LLAVIPQETP LQDAFRAADD ILRQGVQGIS
260 270 280 290 300
DIITIPGLVN VDFADVRAVM ADAGSALMGI GVGSGKSRAK EGAIAAISSP
310 320 330 340 350
LLEHSIEGAK GVVLNITGGT DLTLFEVNTA AETIYEVVDP NANIIFGAVI
360 370 380 390 400
DEKMQGEILI TVIATGFTGE SQLSSPGKVT TTQRPPVAPS PSPQSEPPRE
410
NKPPGLDIPD FLQRRRNR
Length:418
Mass (Da):44,020
Last modified:February 10, 2009 - v1
Checksum:i8D80CE91EE4A2BBF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001291 Genomic DNA. Translation: ACK73376.1.
RefSeqiWP_015956956.1. NC_011729.1.

Genome annotation databases

EnsemblBacteriaiACK73376; ACK73376; PCC7424_5023.
KEGGicyc:PCC7424_5023.

Similar proteinsi

Entry informationi

Entry nameiB7KFQ1_CYAP7
AccessioniPrimary (citable) accession number: B7KFQ1
Entry historyiIntegrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: October 25, 2017
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported