ID   B7KDM3_GLOC7            Unreviewed;       865 AA.
AC   B7KDM3;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with Chase sensor {ECO:0000313|EMBL:ACK70325.1};
GN   OrderedLocusNames=PCC7424_1893 {ECO:0000313|EMBL:ACK70325.1};
OS   Gloeothece citriformis (strain PCC 7424) (Cyanothece sp. (strain PCC
OS   7424)).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Aphanothecaceae; Gloeothece; Gloeothece citriformis.
OX   NCBI_TaxID=65393 {ECO:0000313|EMBL:ACK70325.1, ECO:0000313|Proteomes:UP000002384};
RN   [1] {ECO:0000313|Proteomes:UP000002384}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7424 {ECO:0000313|Proteomes:UP000002384};
RX   PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
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DR   EMBL; CP001291; ACK70325.1; -; Genomic_DNA.
DR   RefSeq; WP_012599268.1; NC_011729.1.
DR   AlphaFoldDB; B7KDM3; -.
DR   STRING; 65393.PCC7424_1893; -.
DR   KEGG; cyc:PCC7424_1893; -.
DR   eggNOG; COG4252; Bacteria.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_85_0_3; -.
DR   OrthoDB; 425396at2; -.
DR   Proteomes; UP000002384; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   PANTHER; PTHR33121:SF85; CYCLIC DI-GMP PHOSPHODIESTERASE PDEK-RELATED; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002384};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        349..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        374..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        406..427
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          456..590
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          599..858
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   865 AA;  98867 MW;  968536616313F945 CRC64;
     MKVKPLQKIQ WLVSKMPFLP KKSSLETKAV LSQISFTFVA SLAIAGLVIG VRQSKILQPV
     ELDIYDQMVK LSPQLPADPR LLIIEITEDD IRKQNRWPLS DETINQLINT VQQYDPKVIG
     LDLFRDVPHP PGSDKLTQTL AADNIIAVKK LNDDGSSELK LHQGITDERA GFADIPIDFD
     NVLRRYLLYA RVNEKPLYSF ALRVSLKYLN NDHFPFKVHP EALQIGSTVF EDLKADSGSY
     QMEPEEVIGW QILLKYRSDD LEESGRNVAR KISLTEVLQG KLEPSWVKDK IVLIGTTAPS
     EKDMFATPYS QGETINYFMP GVVIHAQMVS QILSTVLDQQ QQFCFFPQWG EFLWIWGWCF
     IGGIVVWRFN SPQYFIGIGL MIISGLWGFG FLVFTQSGWI PVLPPILGLI ATGGTVLIYK
     FVSNYYYDSL TYLPNRRFFV SQLQKMNKHQ KADNSELTAV YFLDIDRFKV INEGLGHEAG
     DFVLLETAQR LQGQLNNKAQ LARVGGDEFA IWLNSLVSID EATEIANYLQ QILNQPFFWK
     GQEIYTSVSI GIAFNRTGAK FNSEELLRDA NIAMYQAKNS GKVHYEMFAS GMREQVINRL
     QIETDLRRSI KQQEFQLFYQ PIISLKTGKI AGVEALVRWK SVKRGFISPG EFIPIAEETG
     LIIPLGEWIL QEACSQMRQW HQQFSQNPPL FISVNLSGRQ FSQPNLVQQV QYILETINLE
     RNTLKLEITE SMMMNDVEAA IDLLRRLKDL GLRLSIDDFG TGYSNLSYLH RFPIDTLKID
     QSFVRRMNSQ ESQDRYAQIV RTVIMLGHNL ELDVIAEGIE TEEQMHILKS LGCEYGQGYY
     FAKPLPSPEV TELLKKDPQW LTFKP
//