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Protein

16S rRNA (cytosine(967)-C(5))-methyltransferase

Gene

PCC7424_3045

Organism
Cyanothece sp. (strain PCC 7424) (Synechococcus sp. (strain ATCC 29155))
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei291S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei318S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei335S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei388NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotation, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciCSP65393:G1GUC-3024-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
16S rRNA (cytosine(967)-C(5))-methyltransferaseSAAS annotation (EC:2.1.1.176SAAS annotation)
Gene namesi
Ordered Locus Names:PCC7424_3045Imported
OrganismiCyanothece sp. (strain PCC 7424) (Synechococcus sp. (strain ATCC 29155))Imported
Taxonomic identifieri65393 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesCyanothecaceaeCyanothece
Proteomesi
  • UP000002384 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi65393.PCC7424_3045

Structurei

3D structure databases

ProteinModelPortaliB7KB91
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini176 – 450SAM_MT_RSMB_NOPInterPro annotationAdd BLAST275

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni267 – 273S-adenosyl-L-methionine bindingPROSITE-ProRule annotation7

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CYJ Bacteria
COG0144 LUCA
HOGENOMiHOG000037300
KOiK03500
OMAiLRVNRQH
OrthoDBiPOG091H02E2

Family and domain databases

Gene3Di1.10.940.10, 1 hit
InterProiView protein in InterPro
IPR001678 MeTrfase_RsmB/NOP2
IPR035926 NusB-like_sf
IPR006027 NusB_RsmB_TIM44
IPR023267 RCMT
IPR004573 rRNA_ssu_MeTfrase_B
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PF01029 NusB, 1 hit
PRINTSiPR02008 RCMTFAMILY
SUPFAMiSSF48013 SSF48013, 1 hit
SSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00563 rsmB, 1 hit
PROSITEiView protein in PROSITE
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

B7KB91-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFKEKNPRQ LALIILRDIY QKEAYTDLAL DQGIKRADLG NLDRGLVTEL
60 70 80 90 100
VYGIVRRQRT LDEIISQLGT KKANQQPPDL RLILHIGLYQ LRYLDQIPPS
110 120 130 140 150
AAVNTSVELA KKNKLGKLSG VVNGILRQYD RIKEQGKDPL KFPSDPVNHL
160 170 180 190 200
GVLHSFPNWI IQLWLDEFGQ EQTEQLCEWF NQPAMIDIRV NLLKTTVEKV
210 220 230 240 250
ASIFSDVGVK VKPIPHLPQS LRLIGGTRSI QQLPGFEEGW WTVQDSSAQL
260 270 280 290 300
VTHLLDPQPD EIIIDACAAP GGKTTHIAQL MGDRGTIWAC DRVPSRLRKV
310 320 330 340 350
QQNAERLQLN SIRICEGDSR HLTQFRETAD RVLLDAPCSG LGTLHKRPDI
360 370 380 390 400
RWRQTPEKIA ELSQLQTELL EETATWVKPK GILVYATCTL NPLENERVIA
410 420 430 440 450
AFLDRHPSWH IQTPSSDNTV AAFATPSGWI KVLPHQHQMD GFFMVKLVKG

LE
Length:452
Mass (Da):51,135
Last modified:February 10, 2009 - v1
Checksum:iFC4FB314BB1EC339
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001291 Genomic DNA Translation: ACK71447.1
RefSeqiWP_015955044.1, NC_011729.1

Genome annotation databases

EnsemblBacteriaiACK71447; ACK71447; PCC7424_3045
KEGGicyc:PCC7424_3045

Similar proteinsi

Entry informationi

Entry nameiB7KB91_CYAP7
AccessioniPrimary (citable) accession number: B7KB91
Entry historyiIntegrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: May 23, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health