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B7K947 (B7K947_CYAP7) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetylornithine aminotransferase HAMAP-Rule MF_01107

Short name=ACOAT HAMAP-Rule MF_01107
EC=2.6.1.11 HAMAP-Rule MF_01107
Gene names
Name:argD HAMAP-Rule MF_01107
Ordered Locus Names:PCC7424_4452 EMBL ACK72816.1
OrganismCyanothece sp. (strain PCC 7424) (Synechococcus sp. (strain ATCC 29155)) [Complete proteome] [HAMAP] EMBL ACK72816.1
Taxonomic identifier65393 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesCyanothece

Protein attributes

Sequence length441 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

N(2)-acetyl-L-ornithine + 2-oxoglutarate = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate. HAMAP-Rule MF_01107

Cofactor

Binds 1 pyridoxal phosphate per subunit By similarity. HAMAP-Rule MF_01107

Pathway

Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 4/4. HAMAP-Rule MF_01107

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01107

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01107.

Miscellaneous

May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis By similarity. HAMAP-Rule MF_01107

Sequence similarities

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. HAMAP-Rule MF_01107

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region259 – 2624Pyridoxal phosphate binding By similarity HAMAP-Rule MF_01107

Sites

Binding site1641Pyridoxal phosphate; via carbonyl oxygen By similarity HAMAP-Rule MF_01107
Binding site1671N2-acetyl-L-ornithine By similarity HAMAP-Rule MF_01107
Binding site3151N2-acetyl-L-ornithine By similarity HAMAP-Rule MF_01107
Binding site3161Pyridoxal phosphate By similarity HAMAP-Rule MF_01107

Amino acid modifications

Modified residue2881N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01107

Sequences

Sequence LengthMass (Da)Tools
B7K947 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: CD422F6B80D664EA

FASTA44147,741
        10         20         30         40         50         60 
MLNISTSQTL PQVPKLITPL PGKRASELIN RDNAVTSPSY TRDYPLVVAR GQGCMIEDVD 

        70         80         90        100        110        120 
GNVFLDMTAG IAVTATGHCH PQVVEAIQYQ STQLVHMSGT DFYYAPMVDL AEKLAEKAPF 

       130        140        150        160        170        180 
PTPVTGSRAK VFFTNSGAES TECAIKLARY YTGRSRLIAF LGAFHGRTYG AMSLTGSKRV 

       190        200        210        220        230        240 
QRQGFGPLVP GVTHIPYGTH AGLDDLEEKL FTSIVPPDEV AAIMVEPIQG EGGYLVPEDG 

       250        260        270        280        290        300 
FLERIRSICD RYGILMIVDE VQAGMGRTGK LFAIEHWGIM PDMITLAKGI ASGLPLGAVL 

       310        320        330        340        350        360 
SRPELMTWPP GSHATTFGGN PIACAAGKVT LDLLEGGLME NATQRGEELL LGLTQLSQRF 

       370        380        390        400        410        420 
DRLSLPRGKG LMIGIDLLDR EGNLDPVLRN YVLNEAFYRG LLLLGCGKAA IRFCPPLVIS 

       430        440 
GEQIEVALKI LAEILEEVVR R 

« Hide

References

[1]"Novel metabolic attributes of the genus Cyanothece, comprising a group of unicellular nitrogen-fixing Cyanobacteria."
Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H., Sherman L.A., Pakrasi H.B.
MBio 2:E214-E214(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7424.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001291 Genomic DNA. Translation: ACK72816.1.
RefSeqYP_002379684.1. NC_011729.1.

3D structure databases

ProteinModelPortalB7K947.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING65393.PCC7424_4452.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACK72816; ACK72816; PCC7424_4452.
GeneID7110318.
KEGGcyc:PCC7424_4452.
PATRIC21557920. VBICyaSp136448_4556.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0160.
HOGENOMHOG000020206.
KOK00823.
OMAEGTPIVQ.
OrthoDBEOG6QVRHN.
ProtClustDBPRK05769.

Enzyme and pathway databases

BioCycCSP65393:GJP7-4502-MONOMER.
UniPathwayUPA00068; UER00109.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
HAMAPMF_01107. ArgD_aminotrans_3.
InterProIPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR004636. Trfase_AcOrn/SuccOrn_fam.
[Graphical view]
PANTHERPTHR11986. PTHR11986. 1 hit.
PfamPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMSSF53383. SSF53383. 1 hit.
PROSITEPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB7K947_CYAP7
AccessionPrimary (citable) accession number: B7K947
Entry history
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: February 19, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)