ID   B7K812_GLOC7            Unreviewed;       651 AA.
AC   B7K812;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   RecName: Full=protein-serine/threonine phosphatase {ECO:0000256|ARBA:ARBA00013081};
DE            EC=3.1.3.16 {ECO:0000256|ARBA:ARBA00013081};
GN   OrderedLocusNames=PCC7424_0026 {ECO:0000313|EMBL:ACK68500.1};
OS   Gloeothece citriformis (strain PCC 7424) (Cyanothece sp. (strain PCC
OS   7424)).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Aphanothecaceae; Gloeothece; Gloeothece citriformis.
OX   NCBI_TaxID=65393 {ECO:0000313|EMBL:ACK68500.1, ECO:0000313|Proteomes:UP000002384};
RN   [1] {ECO:0000313|Proteomes:UP000002384}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7424 {ECO:0000313|Proteomes:UP000002384};
RX   PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:20629, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC         COMP:11604, ChEBI:CHEBI:15377, ChEBI:CHEBI:29999, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:83421; EC=3.1.3.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00001512};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC         phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC         COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC         ChEBI:CHEBI:61977; EC=3.1.3.16;
CC         Evidence={ECO:0000256|ARBA:ARBA00001482};
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DR   EMBL; CP001291; ACK68500.1; -; Genomic_DNA.
DR   RefSeq; WP_012597451.1; NC_011729.1.
DR   AlphaFoldDB; B7K812; -.
DR   STRING; 65393.PCC7424_0026; -.
DR   KEGG; cyc:PCC7424_0026; -.
DR   eggNOG; COG0631; Bacteria.
DR   eggNOG; COG2093; Bacteria.
DR   HOGENOM; CLU_025251_0_0_3; -.
DR   OrthoDB; 495860at2; -.
DR   Proteomes; UP000002384; Chromosome.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR   CDD; cd00143; PP2Cc; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR025874; DZR.
DR   InterPro; IPR015655; PP2C.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR47992:SF267; ALPHABET, ISOFORM E; 1.
DR   PANTHER; PTHR47992; PROTEIN PHOSPHATASE; 1.
DR   Pfam; PF12773; DZR; 1.
DR   Pfam; PF13672; PP2C_2; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SMART; SM00332; PP2Cc; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002384};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          387..644
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
SQ   SEQUENCE   651 AA;  73798 MW;  AE7D9CFCE5FF78FD CRC64;
     MLICPQCQYD NPNHSQSCQR CGVSLAEKPC PECGTMVSFE EQNCPNCGAF TATRWWALIT
     PNSPSLSALE TRYLDPGERY RLIMESDLNL PFPLPPQTPD KDLGFQALVM DCQPLQKSVL
     KSLLEQQEEW LNAEDNPQEE NSDRRTSLWH QIGIPQRAFP YLKTRQFSPI IPDIHEAWHD
     GNQEVILLDD RISWQLLSQF WAREELPMLQ IVYWLNEMAS LWTPLTEVGC CQSLLVENNL
     RVDEDQSFGL LRLYEDRDDR QPTLQDLGRM WQQLLHQSKS DKKEALDQLL KDLISGQINQ
     VEQLCLQLQY LAEQEQLTSD EVGKKPLFSE DSDDDYGDVD TVPLPSNFFQ EDDSFDTDAE
     HETIIEGCTT EEFSTADLPM QLLSITDVGH TDTGRLRRHN EDHFALLSDV TKHHSNRGQT
     IRARGLYIVC DGMGGHASGE VASAIAVKTL QDFFATHWEK GLPDAETIEK AIFLANDAIY
     KVNQDKDSYG AGRMGTTLVM MLLEGTQVAI AHVGDSRIYQ INRKWGLQQL TVDHEVGQKA
     VQEGVEPQIA YSRPDAYQLT QALGPHESQY IKPDIKYLDL HEDTLLLLCS DGLSDNKFLE
     IHYSSCLTPL ISSGANLDEG LEKLFALANQ KNGHDNITAI LVRIKLQPCF D
//