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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Cyanothece sp. (strain PCC 7424) (Synechococcus sp. (strain ATCC 29155))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei194 – 1941UniRule annotation
Active sitei668 – 6681UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciCSP65393:GJP7-4288-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:PCC7424_4238Imported
OrganismiCyanothece sp. (strain PCC 7424) (Synechococcus sp. (strain ATCC 29155))Imported
Taxonomic identifieri65393 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesCyanothece
ProteomesiUP000002384: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi65393.PCC7424_4238.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 3 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7K6Q9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLVQVSTT PLQFFSTSDL FLQDRLKLVE ELWEEVLQAE CGQELVALLK
60 70 80 90 100
KLRAICCEQG QAQKALEDSI TQLIEQLDLV EAVRTSRAFA LYFQLINIVE
110 120 130 140 150
QHYEQRDQQL SRRATYQESP VKTKNGNNSE SPSLFSSAFG ANWVERSWTD
160 170 180 190 200
DNQNQQKAGT LHWLFPYLKQ LNVPPQQIQR LLNQLDIRLV FTAHPTEIVR
210 220 230 240 250
HTIRRKQRRI AHILQKLDQA EETFRGMGLT NSWEAEQLKE QFKEEIRLWW
260 270 280 290 300
RTDELHQFKP TVLDEVDYAL HYFNEVLFQA LPQLALRLKQ TLKGAFPRLE
310 320 330 340 350
PPKNNFCYFG SWVGGDRDGN PFVTPEVTWA TACYQRNVVI EKYLQTVDEL
360 370 380 390 400
SNILSPSLHW CNVLPDLLDS LEKDRVQMPE IYTQLAIRYR QEPYRLKLAY
410 420 430 440 450
IKKRLENTQD RNNRLANPNE RLLIFKTGNP NIYHNKEELS EELQLIRRNL
460 470 480 490 500
EASGLTCQEL ENLICQVEIY GFNLTQLDFR QESSCHSDAI NEIAEYLQIL
510 520 530 540 550
PKPYNQLSEA ERTAWLIEEL KTRRPLIPQE MPFSEKTCEV IETLKMLRLL
560 570 580 590 600
QQEFGLEICH TYIISMTNDV SDVLEVMLLA QEAGLYDPAT SSITIRIVPL
610 620 630 640 650
FETVEDLKRA PEIMRALFEM TLYRAALAGG YQYLAKDQGQ EIIGELQPPL
660 670 680 690 700
LQPPNLQEIM VGYSDSNKDS GFLSSNWEIH KAQKALQKVA KGYGIDLRLF
710 720 730 740 750
HGRGGSVGRG GGPAYAAILA QPTGTINGRI KITEQGEVLA SKYSLPELAL
760 770 780 790 800
YNLETIVTAV IQSSLLGCGF DDIQVWNEIM EDLAGCARKA YRSLIYEDPD
810 820 830 840 850
FIDFFMSVTP IPEISQLQIS SRPARRKSGK KDLSTLRAIP WVFSWTQTRF
860 870 880 890 900
LLPAWYGVGT ALEQFINREP EEHLKLLRYF YLKWPFFRMV ISKVEMTLSK
910 920 930 940 950
VDLQIAHHYV KELSKPEDLE RFERVFNQIS EEYHRTCRLV LDITENERLL
960 970 980 990 1000
DGDPTLQRSV QLRNGTIVPL GFLQVSLLKR LRQYNAQAES GVIHFRYSKE
1010 1020
ELLRGALLTI NGIAAGMRNT G
Length:1,021
Mass (Da):117,843
Last modified:February 10, 2009 - v1
Checksum:iFB7805B7E50A78AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001291 Genomic DNA. Translation: ACK72608.1.
RefSeqiWP_015956193.1. NC_011729.1.
YP_002379476.1. NC_011729.1.

Genome annotation databases

EnsemblBacteriaiACK72608; ACK72608; PCC7424_4238.
GeneIDi7108159.
KEGGicyc:PCC7424_4238.
PATRICi21557490. VBICyaSp136448_4341.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001291 Genomic DNA. Translation: ACK72608.1.
RefSeqiWP_015956193.1. NC_011729.1.
YP_002379476.1. NC_011729.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi65393.PCC7424_4238.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACK72608; ACK72608; PCC7424_4238.
GeneIDi7108159.
KEGGicyc:PCC7424_4238.
PATRICi21557490. VBICyaSp136448_4341.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciCSP65393:GJP7-4288-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 3 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Novel metabolic attributes of the genus Cyanothece, comprising a group of unicellular nitrogen-fixing Cyanobacteria."
    Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H., Sherman L.A., Pakrasi H.B.
    MBio 2:E214-E214(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 7424Imported.

Entry informationi

Entry nameiB7K6Q9_CYAP7
AccessioniPrimary (citable) accession number: B7K6Q9
Entry historyi
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: March 4, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.