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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Cyanothece sp. (strain PCC 8801) (Synechococcus sp. (strain PCC 8801 / RF-1))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei192GTPUniRule annotation1
Binding sitei196GTPUniRule annotation1
Binding sitei240GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi74 – 78GTPUniRule annotation5
Nucleotide bindingi161 – 163GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:PCC8801_4253Imported
OrganismiCyanothece sp. (strain PCC 8801) (Synechococcus sp. (strain PCC 8801 / RF-1))Imported
Taxonomic identifieri41431 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesCyanothecaceaeCyanothece
Proteomesi
  • UP000008204 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi41431.PCC8801_4253.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 258TubulinInterPro annotationAdd BLAST193
Domaini260 – 377Tubulin_CInterPro annotationAdd BLAST118

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK. Bacteria.
COG0206. LUCA.
HOGENOMiHOG000049094.
KOiK03531.
OMAiMRAVKGI.
OrthoDBiPOG091H02KK.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR020805. Cell_div_FtsZ_CS.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR037103. Tubulin/FtsZ_C_sf.
IPR036525. Tubulin/FtsZ_GTPase_sf.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.
PROSITEiView protein in PROSITE
PS01134. FTSZ_1. 1 hit.
PS01135. FTSZ_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B7K6C4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTMIFNDKLA LNHSGLNNNE SSESLSALDN YHIHNSSLSL SHSNESSETP
60 70 80 90 100
REDIRRNQIV PNNVAKIKVI GVGGGGCNAV NRMIESSLTG IEFWAINTDA
110 120 130 140 150
QALSQSAASQ RLQIGQKLTR GLGAGGNPSI GTQAAEESRD EIAQALENTD
160 170 180 190 200
LVFITAGMGG GTGTGAAPIV AEVAKEMGCL TVGVVTRPFT FEGRRRTSQA
210 220 230 240 250
SQGVEKLQNN VDTLIVIPNN QLLQVIPPDT PLQQAFLAAD NILRQGVQGI
260 270 280 290 300
SDIITIPGLV NVDFADVRAV MADAGSALMG LGIGSGKSRA SDAAVAAISS
310 320 330 340 350
PLLEHSIKGA RGVVFNITGG DDLTLHEVNT AAETIFEVVD PDANIIFGAV
360 370 380 390 400
IDPTLQGEVI ITVIATGFTG ESEGSGTTKV APIATPTPRK APERTVIPEP
410 420
EPEPPKSTGL DIPDFLQKRR FPPRG
Length:425
Mass (Da):44,506
Last modified:February 10, 2009 - v1
Checksum:i7796AAB41C45E1CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001287 Genomic DNA. Translation: ACK68177.1.
RefSeqiWP_015785230.1. NC_011726.1.

Genome annotation databases

EnsemblBacteriaiACK68177; ACK68177; PCC8801_4253.
KEGGicyp:PCC8801_4253.

Similar proteinsi

Entry informationi

Entry nameiB7K6C4_CYAP8
AccessioniPrimary (citable) accession number: B7K6C4
Entry historyiIntegrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: October 25, 2017
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported