ID   B7K4S0_RIPO1            Unreviewed;       967 AA.
AC   B7K4S0;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   SubName: Full=Putative PAS/PAC sensor protein {ECO:0000313|EMBL:ACK66576.1};
GN   OrderedLocusNames=PCC8801_2570 {ECO:0000313|EMBL:ACK66576.1};
OS   Rippkaea orientalis (strain PCC 8801 / RF-1) (Cyanothece sp. (strain PCC
OS   8801)).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Aphanothecaceae; Rippkaea; Rippkaea orientalis.
OX   NCBI_TaxID=41431 {ECO:0000313|EMBL:ACK66576.1, ECO:0000313|Proteomes:UP000008204};
RN   [1] {ECO:0000313|Proteomes:UP000008204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 8801 {ECO:0000313|Proteomes:UP000008204};
RX   PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP001287; ACK66576.1; -; Genomic_DNA.
DR   RefSeq; WP_012595843.1; NC_011726.1.
DR   AlphaFoldDB; B7K4S0; -.
DR   STRING; 41431.PCC8801_2570; -.
DR   KEGG; cyp:PCC8801_2570; -.
DR   eggNOG; COG2202; Bacteria.
DR   eggNOG; COG2208; Bacteria.
DR   eggNOG; COG3829; Bacteria.
DR   eggNOG; COG5000; Bacteria.
DR   HOGENOM; CLU_000445_114_10_3; -.
DR   OrthoDB; 9802500at2; -.
DR   Proteomes; UP000008204; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd06225; HAMP; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 6.10.340.10; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 3.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR033479; dCache_1.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF02743; dCache_1; 1.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF13426; PAS_9; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00304; HAMP; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 2.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF158472; HAMP domain-like; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50885; HAMP; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008204};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        355..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          375..427
FT                   /note="HAMP"
FT                   /evidence="ECO:0000259|PROSITE:PS50885"
FT   DOMAIN          582..613
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          640..692
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   COILED          419..456
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          694..721
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   967 AA;  108952 MW;  F88DAD7A03356AEE CRC64;
     MLITLLQKFQ YKIPLRTVLV VPFVIQIVGA VGLVGYLSFR NGQKAVEDLA GQLTNEVSNV
     IIERLNSYLG TPHLVNQLNK NALNLGQLNL QNIKAIERHF WQQAQVFELV SKIQFAGVDG
     KFIGLAINDD GTLDYQERDR SGDLQTYAIN SQGNRRERLR TYIGFDARLQ PWYIASERAG
     KPVWSQIYPW VSPPTLAITL GESYYDKNGK FQGVLATDLT LLQISDFLRS LKIGRSGKTF
     IIESSGQLVA SSSAKSPFLM VDNQPQRLSA TNLEDSLIRP AAFYLQKTLG NIKTASPEDI
     IPIDIPQKLK FKIHGKHHFM KVLPFQDDFG LDWYIVIVVP ESDFMQQIEA NNKTTFALVI
     AALILATTLG LLTSRWIVEL ILQLNQAAQQ IAEGNLKTKV NIKGIKELES LGITFNVMAN
     QIKDYFEALE AKNEDLEQAK ADLLEAKEKL ETILDAVPGS ISWIDSQGFY LGVNRYLSDK
     WNLPAEEFIG KPIGFLQGND HLIEFLFSFL ESSKDADSQV VEITFNDCLE YYLIAAQKYQ
     GGNATVSIGI NITERKKAEE KLTQTVKELS DIKYALDQLA IVTITDAQGN INYVNDKFCE
     VSQYSPEELI GNNHRILKSG YHDRAFYKEL WSTISSGQIW QGEIKNKTKD GAFYWVNSTI
     IPFLDKTGRP FQYLSIRTEI TARKELEQTL ESIVSKRTAQ LAAANQEITD LNNKLRLENV
     RMSAELNVVF QMQQMILPKV EELRGIEGLE LAGFMKPAAE VGGDYYDVLH HDGIVTLGIG
     DVTGHGLESG ILMVMTQTAV RTLKEIGETD PIRFLSALNR TIYQNLQRMN SDKNLSLGIL
     HYYQRQLRIS GQHEEILLVR SGGKIERINT IDLGFPIGLD HDISHFVDQV CVELNPGDGV
     ILYTDGITEA KDINRNFYGL NRLCDVVSQS WQKSAQEIQE AVIEDVYQHI GEQKVFDDIT
     LLVLKQK
//