ID   B7K4E7_RIPO1            Unreviewed;       715 AA.
AC   B7K4E7;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   SubName: Full=Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ACK65412.1};
GN   OrderedLocusNames=PCC8801_1350 {ECO:0000313|EMBL:ACK65412.1};
OS   Rippkaea orientalis (strain PCC 8801 / RF-1) (Cyanothece sp. (strain PCC
OS   8801)).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Aphanothecaceae; Rippkaea; Rippkaea orientalis.
OX   NCBI_TaxID=41431 {ECO:0000313|EMBL:ACK65412.1, ECO:0000313|Proteomes:UP000008204};
RN   [1] {ECO:0000313|Proteomes:UP000008204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 8801 {ECO:0000313|Proteomes:UP000008204};
RX   PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
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DR   EMBL; CP001287; ACK65412.1; -; Genomic_DNA.
DR   RefSeq; WP_012594686.1; NC_011726.1.
DR   AlphaFoldDB; B7K4E7; -.
DR   STRING; 41431.PCC8801_1350; -.
DR   KEGG; cyp:PCC8801_1350; -.
DR   eggNOG; COG0745; Bacteria.
DR   eggNOG; COG3829; Bacteria.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_50_3; -.
DR   OrthoDB; 9813903at2; -.
DR   Proteomes; UP000008204; Chromosome.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   CDD; cd19920; REC_PA4781-like; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008204}.
FT   DOMAIN          8..124
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          157..230
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          235..287
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          319..452
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          463..715
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   MOD_RES         57
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   715 AA;  80975 MW;  A7DA8CCFAD5C7BD5 CRC64;
     MTDSTKGCLL IVDDLPDNLR LLRDTLQGQG YKVRSCITGM MALRAAKAAV TDLILLDIKL
     PDYDGYEICR RLKADEQTAH IPVIFLSALN ETFDKVQGFT VGGADYITKP FQIEEVLARV
     ATHLSIQRLQ TSLQEKNLSL IQEIEEHRRT KEALFCEKEL AQVTLKSIGD AVITTDAKGY
     VTYLNPIAEY LTGWAEKEAQ GVHLFEVFEI VNEFTKEIVE NPIIQALDEV RIVNLAKNTI
     LISRDGTEYP IDDSAAPIQD SNGQVIGAVI VFRDVTEARS LNRQLSWQAS HDSLTGLINR
     LGFEQKLEEA LLSAKKENQH HVLCYLDLDQ FKVVNDTCGH AAGDELLRQI THLLQQRVRT
     SDTLARLGGD EFAFLLHQCS LEKATEIAET FRELIEKFRF CWNNKTFSIG VSIGVVEIDK
     NSKDKNSVLA LADAACYAAK GKGRNCVQVY QVDNHELLKQ RKERQWVVQI NQALEDNRFR
     LYSQKITPLN SHLKPIYYEI LLRLLDDNGQ LVSPGNFLPA AERYGLMPAI DRWVISTFLK
     KYDNYYHQTV NKSDFEQNLY AINLSGASIN SEQFLEFLKE QLTNSKIPLK NLCFEITETT
     AIANFDQAIE LINELQQLGC CFAIDDFGHG MNSFDYLKHF PVNYLKIDGS FVRNLVQSEV
     DQAIVESFNR IGHIMNFQTI AEFVENAAIL SKIEAIGLDY AQGYVIAKPV PFEFK
//