ID   B7K4E5_RIPO1            Unreviewed;       840 AA.
AC   B7K4E5;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 75.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ACK65410.1};
GN   OrderedLocusNames=PCC8801_1348 {ECO:0000313|EMBL:ACK65410.1};
OS   Rippkaea orientalis (strain PCC 8801 / RF-1) (Cyanothece sp. (strain PCC
OS   8801)).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Aphanothecaceae; Rippkaea; Rippkaea orientalis.
OX   NCBI_TaxID=41431 {ECO:0000313|EMBL:ACK65410.1, ECO:0000313|Proteomes:UP000008204};
RN   [1] {ECO:0000313|Proteomes:UP000008204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 8801 {ECO:0000313|Proteomes:UP000008204};
RX   PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
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DR   EMBL; CP001287; ACK65410.1; -; Genomic_DNA.
DR   RefSeq; WP_012594684.1; NC_011726.1.
DR   AlphaFoldDB; B7K4E5; -.
DR   STRING; 41431.PCC8801_1348; -.
DR   KEGG; cyp:PCC8801_1348; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_20_3; -.
DR   OrthoDB; 415644at2; -.
DR   Proteomes; UP000008204; Chromosome.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00989; PAS; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00240; FHA; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008204}.
FT   DOMAIN          29..89
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
FT   DOMAIN          285..330
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          440..573
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          582..836
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   840 AA;  95058 MW;  219F9AC43ECDEEFE CRC64;
     MSNASEVRHV LIISDSKSRR IVPLTESTYS IGRDPNTNIL LYDRQVSRHH ATILQVTNDQ
     GEQPLYRIID GDLQGKRSTN GITINGKNCL SHDLKSGDEI RFGSKCYANY HIIINSEDLD
     SLKEEECQSD TLVKSDSLDL SLFKTSMNQT DEEIKPDFLE IGQKNSNKIA LEENYLESPD
     DLASLTQGNP NPIIEINFEG EITYLNISAR VKFPTLQQDL SKHPILEGLI VGSSTQKGTS
     FVREIQIEHA FFEQHIHYLE DKKAIRLYLF DITKYKTREA KLTTGKDRYR LFVEQATEGI
     LLVNCETQYI IEANQAYCHL LGYTTAEIIG LSLHQLIAID KAIIDQELSC VTSETPYFIK
     ESIHRHKDGS LISVSGKINR TTYQGQEIFC LVIRDIRDRK QAEEQLQYQA LHDPLTNLPN
     RESFNQKLVL ALDHAQRYQH LMAVMFVDID SFTNINNTLG PSIGDRLLDS FGKRLSSCVR
     TGDTVARWGS DEFVLLLPQI KNTEDTVKLA QRIFDNLQVP FILDDHRLPV KCSIGIAVYP
     QDGEAGETLL KNAGTALGRT KEQGRNHYQF YNPNLSSEAA LLLRLESLLH QGLEKKQFFL
     HYQPQINLKT KKVVGMEALL RWEHPSLGII NPQKFIPLAE KTDLILHLGK WVLQTACEQN
     ISWQKDGLPP ISIGVNLSAR EVQQPNLAEV VARVLNDTGL DPQWLELELT EMSLRQHLTQ
     ARKSLRDLKN LGVRIALDDF GTGFSSLGYL QQFSFRTLKL HQAFIRDLRG TSEELGIISA
     ALAISKGFNM RIVAEGVETE EQLKILSNLN CEEIQGYCFS RPLPVKEATV FLQNAARGSL
//