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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Cyanothece sp. (strain PCC 8801) (Synechococcus sp. (strain PCC 8801 / RF-1))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei194 – 1941UniRule annotation
Active sitei671 – 6711UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciCSP41431:GHLK-3510-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:PCC8801_3469Imported
OrganismiCyanothece sp. (strain PCC 8801) (Synechococcus sp. (strain PCC 8801 / RF-1))Imported
Taxonomic identifieri41431 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesCyanothece
ProteomesiUP000008204 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi41431.PCC8801_3469.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 3 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7K0F0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLLESSSS IVEEINIFST SDLFLRQRLK LVEELWEAVL RAECGQELVD
60 70 80 90 100
LLKQLRTMCS PEGQLTDITQ TPITAVIEQL ELNESIRAAR AFALYFQLIN
110 120 130 140 150
IVEQHYEQRD QQLTRRANYC DIDSKPANNH GESSTNPSIG HHLVERSWMD
160 170 180 190 200
SENTSEKGGT FHWLFPHLKE LNVPPQQIQR LLDQLDIRLV FTAHPTEIVR
210 220 230 240 250
HTIRRKQRRI VNILRRLDRA EEAFRGMGLS NSWEAQSAIE QLTEEIRLWW
260 270 280 290 300
RTDELHQFKP SVLDEVDYAL HYFDEVLFEV LPQLSQRLQQ SLKSSFPWLR
310 320 330 340 350
PPKNTFCRFG SWVGGDRDGN PFVTPEVTWK TACYQRNMVL KKYLESIRDL
360 370 380 390 400
TEILSASLHW SNVSQDLLDS LERDRVQMPE IYDELAIRYR HEPYRLKLAY
410 420 430 440 450
IEKRLQNTRD RNNRLANPDQ RQQLLYREEE NIYHSGEEFW QELELIKRNL
460 470 480 490 500
EETGLNCLEL NNLLIQAEMF GFNLTQLDFR QDSSRHADAI EEIAEYLNIL
510 520 530 540 550
PKPYTQLSEA EKTQWLIQEL KTRRPLIPTG MQFKKPENSE TVETLQMLRY
560 570 580 590 600
LQQEFGLEIC QTYIISMTNY VSDVLEVLLL AKEAGLYDPA TSTTTIRIVP
610 620 630 640 650
LFETVDDLKR APEVMEDLFK LPLYRASLAG GYDQLQPSET PSQGAVKSLN
660 670 680 690 700
LPALQPTNLQ EIMVGYSDSN KDSGFLSSNW EIHKAQKALQ NMAQRYGVDL
710 720 730 740 750
RLFHGRGGSV GRGGGPAYAA ILAQPSSTIN GRIKITEQGE VLASKYSLGD
760 770 780 790 800
LALYNLETVS TAVIQASLLG SGFDDINPWN EIMEDLAERA RKAYRGLIYE
810 820 830 840 850
QPDFLDFFLS VTPIPEISQL QISSRPARRK SGKADLSSLR AIPWVFSWTQ
860 870 880 890 900
SRFLLPAWYG VGTALQSFVD EEPEENLKLL RYFYLKWPFF KMVVSKVEMT
910 920 930 940 950
LSKVDLQIAH HYVRELSKAE DKERFERVFE EISQEYHRTR DVILNITNHQ
960 970 980 990 1000
RLLDSDLSLQ RSVQLRNGTI VPLGFLQVAL LKRLRQYSNQ AQSGVIHFRY
1010 1020
SKEELLRGAM LTINGIAAGM RNTG
Length:1,024
Mass (Da):118,369
Last modified:February 9, 2009 - v1
Checksum:i48E02B37E1609400
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001287 Genomic DNA. Translation: ACK67434.1.
RefSeqiYP_002373590.1. NC_011726.1.

Genome annotation databases

EnsemblBacteriaiACK67434; ACK67434; PCC8801_3469.
KEGGicyp:PCC8801_3469.
PATRICi21579303. VBICyaSp125535_3656.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001287 Genomic DNA. Translation: ACK67434.1.
RefSeqiYP_002373590.1. NC_011726.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi41431.PCC8801_3469.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACK67434; ACK67434; PCC8801_3469.
KEGGicyp:PCC8801_3469.
PATRICi21579303. VBICyaSp125535_3656.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiFTSNWEL.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciCSP41431:GHLK-3510-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 3 hits.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Novel metabolic attributes of the genus Cyanothece, comprising a group of unicellular nitrogen-fixing Cyanobacteria."
    Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H., Sherman L.A., Pakrasi H.B.
    MBio 2:E214-E214(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 8801Imported.

Entry informationi

Entry nameiB7K0F0_CYAP8
AccessioniPrimary (citable) accession number: B7K0F0
Entry historyi
Integrated into UniProtKB/TrEMBL: February 9, 2009
Last sequence update: February 9, 2009
Last modified: March 31, 2015
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.