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B7JYL8 (B7JYL8_CYAP8) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO HAMAP-Rule MF_01037
EC=2.1.1.74 HAMAP-Rule MF_01037
Alternative name(s):
Folate-dependent tRNA (uracil-5-)-methyltransferase HAMAP-Rule MF_01037
Folate-dependent tRNA(M-5-U54)-methyltransferase HAMAP-Rule MF_01037
Gene names
Name:trmFO HAMAP-Rule MF_01037
Ordered Locus Names:PCC8801_0806 EMBL ACK64888.1
OrganismCyanothece sp. (strain PCC 8801) (Synechococcus sp. (strain PCC 8801 / RF-1)) [Complete proteome] [HAMAP] EMBL ACK64888.1
Taxonomic identifier41431 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Cyanothece

Protein attributes

Sequence length459 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs By similarity. HAMAP-Rule MF_01037 SAAS SAAS004417

Catalytic activity

5,10-methylenetetrahydrofolate + uridine54 in tRNA + FADH2 = tetrahydrofolate + 5-methyluridine54 in tRNA + FAD. HAMAP-Rule MF_01037 SAAS SAAS004417

Cofactor

FAD By similarity. HAMAP-Rule MF_01037 SAAS SAAS004417

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_01037 SAAS SAAS004417.

Sequence similarities

Belongs to the MnmG family. TrmFO subfamily. HAMAP-Rule MF_01037

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding13 – 186FAD By similarity HAMAP-Rule MF_01037

Sequences

Sequence LengthMass (Da)Tools
B7JYL8 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: 072BE7030E92E378

FASTA45950,805
        10         20         30         40         50         60 
MNDRSTTTIQ VIGGGLAGTE AAWQIAQAGV PVILYEMRPL RTSPAHHSEE LAELVCSNSF 

        70         80         90        100        110        120 
GAMSSDRAAG LLHEELRRLG SIIIQTADQH SVPAGGALAV DRGVFSHALT QTLDNHPLIT 

       130        140        150        160        170        180 
LKRAAIGQIP SEGIVVLTTG PLTTPDLAED LQRFTGMDYL SFFDAASPII VGDSINRDIA 

       190        200        210        220        230        240 
FLASRYDKGE AAYLNCPLTK EQYLHFREEL CQAEQAELKD FERETAQFFE GCLPIEELAK 

       250        260        270        280        290        300 
RGEDTMRYGP LKPVGLFDSR LGDFRDPENK GKRPYGVVQL RQEDKNGQLW NMVGFQTNLK 

       310        320        330        340        350        360 
WGEQKRIFRL IPGLETAEFV RMGVMHRNTF INSPQLLEAT LQFKSRPTLL AAGQLIGTEG 

       370        380        390        400        410        420 
YSAAAAGGWL AGTNAARLAL RLDPLKMPET TMMGALFEFI SSASPKHFQP MPPNFGIIPE 

       430        440        450 
LSHKIGNKRE RYGKYRDRAL ADLETWNNQS VNKRSLCVQ

« Hide

References

[1]"Novel metabolic attributes of the genus Cyanothece, comprising a group of unicellular nitrogen-fixing Cyanobacteria."
Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H., Sherman L.A., Pakrasi H.B.
MBio 2:E214-E214(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 8801.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001287 Genomic DNA. Translation: ACK64888.1.
RefSeqYP_002371044.1. NC_011726.1.

3D structure databases

ProteinModelPortalB7JYL8.
ModBaseSearch...

Protein-protein interaction databases

STRING41431.PCC8801_0806.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACK64888; ACK64888; PCC8801_0806.
GeneID7103150.
KEGGcyp:PCC8801_0806.
PATRIC21573822. VBICyaSp125535_0949.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1206.
HOGENOMHOG000252054.
KOK04094.
OMARFAGQIT.
ProtClustDBPRK05335.

Enzyme and pathway databases

BioCycCSP41431:GHLK-824-MONOMER.

Family and domain databases

HAMAPMF_01037. TrmFO.
InterProIPR004417. Folate-dep_Ribothymidyl_synth.
IPR002218. GIDA-rel.
IPR020595. GIDA-rel_CS.
[Graphical view]
PfamPF01134. GIDA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00137. gid_trmFO. 1 hit.
PROSITEPS01281. GIDA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB7JYL8_CYAP8
AccessionPrimary (citable) accession number: B7JYL8
Entry history
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: May 1, 2013
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info