ID   B7JX23_RIPO1            Unreviewed;       872 AA.
AC   B7JX23;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 63.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with Chase sensor {ECO:0000313|EMBL:ACK65872.1};
GN   OrderedLocusNames=PCC8801_1829 {ECO:0000313|EMBL:ACK65872.1};
OS   Rippkaea orientalis (strain PCC 8801 / RF-1) (Cyanothece sp. (strain PCC
OS   8801)).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Aphanothecaceae; Rippkaea; Rippkaea orientalis.
OX   NCBI_TaxID=41431 {ECO:0000313|EMBL:ACK65872.1, ECO:0000313|Proteomes:UP000008204};
RN   [1] {ECO:0000313|Proteomes:UP000008204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 8801 {ECO:0000313|Proteomes:UP000008204};
RX   PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
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DR   EMBL; CP001287; ACK65872.1; -; Genomic_DNA.
DR   RefSeq; WP_012595144.1; NC_011726.1.
DR   AlphaFoldDB; B7JX23; -.
DR   STRING; 41431.PCC8801_1829; -.
DR   KEGG; cyp:PCC8801_1829; -.
DR   eggNOG; COG4252; Bacteria.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_85_0_3; -.
DR   OrthoDB; 425396at2; -.
DR   Proteomes; UP000008204; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008204};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        45..66
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..379
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        385..406
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        411..431
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          468..602
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          611..870
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   872 AA;  98500 MW;  10B3A5814E0C7004 CRC64;
     MIVKLHQAIR SLVAAAQSNG QSFRVVENRP EAKRNYRPRF LVGSWFSYVP AILLSSGLVT
     LSLFGIKQSG HLQFLELVAY DQMVQMTPSD DQDPRLLLIG ITEQDIKKQK QWPLSDQVIA
     QVLNTLQTYQ PQVIGLDIYR DVPYKPGTED LYKALQANNI VVVKQLPTDN DQGIVPLANI
     PPSRIGFSDF VIDPDNVVRR NLMYGESPSG KVQAVSFALQ VSLKYLKNRG FNVSIKPESE
     ALTIGNVPFT RLKVDSGGYH LPEKEAWGWQ SLLKYRRPDL ARQVTLQQVL DQELDPNWVK
     DKIVLIGVTA SSEKDTFPTP YSAKQTNNFE MPGVMIHGQM VSQILGTILQ GEQQLWFWSQ
     WLEWLWVCGW ALVGGVLVWR LNGLWSLGGA VLMAGVSVWG ISFFVFTQGG WIPLVPGVLG
     LLASGAFVLA YKAIYRTYHD PLTGLPNRRL LIRQIQQVNR SQGSESQKLI AILFLDFDRF
     KTINDGLGHL AGDHLLMQIS RRLQEQSQPQ ILVGRVGGDE FALCLNQISH AQEVTAFADA
     LQKHLSQPFY WQNQEIYITA SIGIALECVG QNFQAGELLR YADIAMYRAK ELGTARHEVF
     VEGMDTQAVE RWQLETDLRA GLQNQEFQLY YQPIISLKTG KIAGFEALVR WVSNKRGFVS
     PGDFIPLAEE TGLIVPLGQW ILQEACQQIQ RWHEQFPEIV PLIMSVNLSG RQFTQPDLVK
     QIQKILDEVN IEGDRLKLEI TESMMMNDVE TAIDLLRRLK GLGLRLSIDD FGTGYSSLSY
     LHRFPVDTLK VDRSFVGRME EGSDSEKYIQ IVRTIISLGH NLDLDVIAEG IETEAQVRVL
     ESLNCEYGQG YYFSKPLSAK DAEELLNQDK EW
//