ID   B7JWK6_RIPO1            Unreviewed;      1143 AA.
AC   B7JWK6;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ACK68347.1};
GN   OrderedLocusNames=PCC8801_4425 {ECO:0000313|EMBL:ACK68347.1};
OS   Rippkaea orientalis (strain PCC 8801 / RF-1) (Cyanothece sp. (strain PCC
OS   8801)).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Aphanothecaceae; Rippkaea; Rippkaea orientalis.
OX   NCBI_TaxID=41431 {ECO:0000313|EMBL:ACK68347.1, ECO:0000313|Proteomes:UP000008204};
RN   [1] {ECO:0000313|Proteomes:UP000008204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 8801 {ECO:0000313|Proteomes:UP000008204};
RX   PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
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DR   EMBL; CP001287; ACK68347.1; -; Genomic_DNA.
DR   RefSeq; WP_015957434.1; NC_011726.1.
DR   AlphaFoldDB; B7JWK6; -.
DR   STRING; 41431.PCC8801_4425; -.
DR   KEGG; cyp:PCC8801_4425; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_20_3; -.
DR   OrthoDB; 442691at2; -.
DR   Proteomes; UP000008204; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 5.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 5.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 5.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF08447; PAS_3; 3.
DR   Pfam; PF13188; PAS_8; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 5.
DR   SMART; SM00091; PAS; 5.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 5.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 4.
DR   PROSITE; PS50112; PAS; 5.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008204};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          107..177
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          181..233
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          248..297
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          300..348
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          349..392
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          455..528
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          527..579
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          580..653
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          655..707
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          740..873
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          882..1138
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   1143 AA;  131471 MW;  DA53C22AE40DA8AA CRC64;
     MVNQLAVPEL IGLSLGSLLI GIIAYLIKDK IDGKKDSVSS IRSLETSEKS LETSEKSLKN
     CQKEWQQAPW KLKPEMTLNT NVKKQLKQEQ QMRRMNIQPS HQELKRVNPH FQNIFNQAKV
     AIALVNLQGK FVQVNQAFCD LIGYTSQELI KLQLSKITHP EERLSDSQWL NQLLKNSCEA
     FSREKRYVKK DGSIIWGQVT VSVMKDQAKK PQYFIVIINA ISDRQETERH RDRFFVMSLD
     LLCIAGFDGY FKTLNPVFER ILGYSSRELL AQPFIEFIHP DDRSTSLAEL ANLRQGKETI
     HFENRYRCRD GSYRWLSWTS APYMEEKLIY AVARDITEEK KIEIALKDSE ERFRQIVTTI
     SDGLIVVNLE GNIRFVNLAA QELFVRSETE LLEHPFGLPI VVDKITEICI QPSRNTLIVA
     EMRSAEITWE GEKGYLISLR NITDSYQANQ KLAESEEKYR KIVETTNEGI WISDHHNKIT
     FVNHQMSEIL GYTVDKMMGM SLLTFIDAAQ LSLVEKSGQK TEQSLPGTHD LKLRRQDGSE
     LWAIVSTNAL FNPEGDYMGT LGLITDITKR KRTEQALYDS EKRLEGILNS LQDVIWSADP
     KTRQSLYLNP AIQLVYGRPM EDFFRDPHLW LCMVHPEDQE LVSHHLKLLE DKGSTEVHYR
     IIRPDGETRW LHSRSRLVYD EQGKSLRIDG INSDITERKQ AEEQLQYNAT HDTLTQLPNR
     LLFMDRLEHA LERRRRYSDP LFAVLFLDLD EFKVINDSLG HALGDELLRE IARRLQKSLR
     ADDTLARLGG DEFTILLEEI HDVKDAIKIA ERIHKDLTRP FNLEGQEIFT NTSIGIALSN
     GEYEAASEIL RDADTAMYRA KAGGKACYAI FDQQMHASAV SRLQLETDLR RAIERQEFLV
     YYQPIISLQH DTLTGFEALI RWQHPQQGLV PPARFIPIAE ETGLIVPIGE WILEQAAQQL
     KIWQTQYRNY ESLKMSVNLS SKQLRDASLL GTIDRILSKT EIDNNALKVE ITESILMENV
     QVAADVLIAL RERNIEICLD DFGTGYSSLS YLHRFPVNTL KIDRSFVMRM RPNDENSEIV
     RAIVSLAHIL GMEIIAEGIE TELQLAQLKW IGCEQGQGYF FAKPLATSEV EALLKNPHYW
     ANL
//