ID   B7JVD9_RIPO1            Unreviewed;       726 AA.
AC   B7JVD9;
DT   10-FEB-2009, integrated into UniProtKB/TrEMBL.
DT   10-FEB-2009, sequence version 1.
DT   27-MAR-2024, entry version 79.
DE   SubName: Full=Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ACK68272.1};
GN   OrderedLocusNames=PCC8801_4350 {ECO:0000313|EMBL:ACK68272.1};
OS   Rippkaea orientalis (strain PCC 8801 / RF-1) (Cyanothece sp. (strain PCC
OS   8801)).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Chroococcales; Aphanothecaceae; Rippkaea; Rippkaea orientalis.
OX   NCBI_TaxID=41431 {ECO:0000313|EMBL:ACK68272.1, ECO:0000313|Proteomes:UP000008204};
RN   [1] {ECO:0000313|Proteomes:UP000008204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 8801 {ECO:0000313|Proteomes:UP000008204};
RX   PubMed=21972240; DOI=10.1128/mBio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
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DR   EMBL; CP001287; ACK68272.1; -; Genomic_DNA.
DR   RefSeq; WP_015957398.1; NC_011726.1.
DR   AlphaFoldDB; B7JVD9; -.
DR   STRING; 41431.PCC8801_4350; -.
DR   KEGG; cyp:PCC8801_4350; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_50_3; -.
DR   OrthoDB; 442691at2; -.
DR   Proteomes; UP000008204; Chromosome.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   CDD; cd00156; REC; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00091; PAS; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50112; PAS; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008204}.
FT   DOMAIN          20..136
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          161..231
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          320..453
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          462..718
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   COILED          140..171
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          297..324
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   MOD_RES         71
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   726 AA;  82841 MW;  157E8BA6A9BDF351 CRC64;
     MSEATCNAPL SSTEVTQSLH LLLLEDVPED VELIVLSLSN ADIEFTYEIA QTATLYQEKL
     QQQTYSAILA DYRLPGFNGL QALKMLQEAG QKIPFILVTG SLGEEAAVEC MKAGVTDYIV
     KDRLFQLPTI LMRSLEEFAL RREQQRVMEE RRQAEIALRA SEKRFRALIE NASDIILIVA
     PDSQLTYASP SVERVLGYDA SSLTGQRFFD LIHPDEQGEI IGFFDKIKET SNLSQLLPDF
     RVRTQKDTWV ILEAIARNLQ DDPAVGGFVV NCHDITERHQ TAEQLRYDAS HDKLTGLANR
     SALLKQLKRA IEQKKRRKED HFALLFLDLD RFKVINDGLG HLMGDQLLKE MAKRLQRCHR
     EGDLLARFGG DEFVFFLKEI RQQEQAIVVA ERIHQALREP FILNHQEVFI SASIGITLSA
     DHYDSPEQML RDADTAMYWA KARGQGGHTI FAPTMHLSAL KQLHLESDLR QAIQRQELVV
     YYQPIFSLDT QKIVGAEALV RWQPPEKPLI PPNDFIPLAE ETGLILEIDH WVLKSACQQL
     YQWQQEFKTL APQFISVNLS PKQFSQPNLT EKIVQTIKET GLAEQCLKIE ITETVFLENS
     TSVLEILCQL QQLNIQICLD DFGTGYSSLS YLHQFPLNSL KLDRTFVSRL GKTNKNDTIV
     RIVATLANEL DLELIAEGIE EIEQIQLLHY LGYQWGQGYC FSPPVDSNSF IEFLIENPMK
     YRIQES
//