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B7JFQ8

- PHNX_BACC0

UniProt

B7JFQ8 - PHNX_BACC0

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Protein

Phosphonoacetaldehyde hydrolase

Gene

phnX

Organism
Bacillus cereus (strain AH820)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Involved in phosphonate degradation.UniRule annotation

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotation

Cofactori

Binds 1 Mg2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei9 – 91NucleophileUniRule annotation
Metal bindingi9 – 91MagnesiumUniRule annotation
Metal bindingi11 – 111Magnesium; via carbonyl oxygenUniRule annotation
Active sitei50 – 501Schiff-base intermediate with substrateUniRule annotation
Metal bindingi183 – 1831MagnesiumUniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphonoacetaldehyde hydrolase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. organic phosphonate catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Ligandi

Magnesium, Metal-binding, Schiff base

Enzyme and pathway databases

BioCyciBCER405535:GHSL-1425-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolaseUniRule annotation (EC:3.11.1.1UniRule annotation)
Short name:
PhosphonataseUniRule annotation
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolaseUniRule annotation
Gene namesi
Name:phnXUniRule annotation
Ordered Locus Names:BCAH820_1414
OrganismiBacillus cereus (strain AH820)
Taxonomic identifieri405535 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000001363: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 264264Phosphonoacetaldehyde hydrolasePRO_1000144826Add
BLAST

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi405535.BCAH820_1414.

Structurei

3D structure databases

ProteinModelPortaliB7JFQ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PhnX family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0637.
HOGENOMiHOG000217971.
KOiK05306.
OMAiGATWEEY.
OrthoDBiEOG6ZH2FH.

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPiMF_01375. PhnX.
InterProiIPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01549. HAD-SF-IA-v1. 1 hit.
TIGR01509. HAD-SF-IA-v3. 1 hit.
TIGR01422. phosphonatase. 1 hit.

Sequencei

Sequence statusi: Complete.

B7JFQ8 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKIEAVIFDW AGTTVDYGCF APLEVFMEIF HKRGVGITAE EARKPMGLLK
60 70 80 90 100
IDHVRALTEM PRIANEWNRI FGQLPTETDI QEMYEEFEEI LFAILPRYAS
110 120 130 140 150
PIHGVKEVIA SLRERGIKIG STTGYTREMM DIVAKEAALQ GYKPDFLVTP
160 170 180 190 200
DDVPAGRPYP WMCYKNAMEL GVYPMNHMIK IGDTVSDMKE GRNAGMWTVG
210 220 230 240 250
VILGSSELGL SEEEVENMDS AELREKIEVV RNRFVENGAH FTIETMQELE
260
SVMERIEKQE LIIS
Length:264
Mass (Da):30,032
Last modified:February 10, 2009 - v1
Checksum:iDE04AD84BE0E9033
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001283 Genomic DNA. Translation: ACK88943.1.
RefSeqiYP_002450365.1. NC_011773.1.

Genome annotation databases

EnsemblBacteriaiACK88943; ACK88943; BCAH820_1414.
GeneIDi7189447.
KEGGibcu:BCAH820_1414.
PATRICi18839684. VBIBacCer122868_1355.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001283 Genomic DNA. Translation: ACK88943.1 .
RefSeqi YP_002450365.1. NC_011773.1.

3D structure databases

ProteinModelPortali B7JFQ8.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 405535.BCAH820_1414.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACK88943 ; ACK88943 ; BCAH820_1414 .
GeneIDi 7189447.
KEGGi bcu:BCAH820_1414.
PATRICi 18839684. VBIBacCer122868_1355.

Phylogenomic databases

eggNOGi COG0637.
HOGENOMi HOG000217971.
KOi K05306.
OMAi GATWEEY.
OrthoDBi EOG6ZH2FH.

Enzyme and pathway databases

BioCyci BCER405535:GHSL-1425-MONOMER.

Family and domain databases

Gene3Di 1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPi MF_01375. PhnX.
InterProi IPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view ]
Pfami PF13419. HAD_2. 1 hit.
[Graphical view ]
SUPFAMi SSF56784. SSF56784. 1 hit.
TIGRFAMsi TIGR01549. HAD-SF-IA-v1. 1 hit.
TIGR01509. HAD-SF-IA-v3. 1 hit.
TIGR01422. phosphonatase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Bacillus cereus AH820."
    Dodson R.J., Durkin A.S., Rosovitz M.J., Rasko D.A., Hoffmaster A., Ravel J., Sutton G.
    Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AH820.

Entry informationi

Entry nameiPHNX_BACC0
AccessioniPrimary (citable) accession number: B7JFQ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: October 1, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3