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Protein

Pyrrolidone-carboxylate peptidase

Gene

pcp

Organism
Bacillus cereus (strain AH820)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Removes 5-oxoproline from various penultimate amino acid residues except L-proline.UniRule annotation

Catalytic activityi

Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei80UniRule annotation1
Active sitei143UniRule annotation1
Active sitei167UniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Thiol protease

Names & Taxonomyi

Protein namesi
Recommended name:
Pyrrolidone-carboxylate peptidaseUniRule annotation (EC:3.4.19.3UniRule annotation)
Alternative name(s):
5-oxoprolyl-peptidaseUniRule annotation
Pyroglutamyl-peptidase IUniRule annotation
Short name:
PGP-IUniRule annotation
Short name:
PyraseUniRule annotation
Gene namesi
Name:pcpUniRule annotation
Ordered Locus Names:BCAH820_3096
OrganismiBacillus cereus (strain AH820)
Taxonomic identifieri405535 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000001363 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001239861 – 215Pyrrolidone-carboxylate peptidaseAdd BLAST215

Proteomic databases

PRIDEiB7JDC3

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

SMRiB7JDC3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase C15 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000242641
KOiK01304
OMAiVCNHVFY

Family and domain databases

CDDicd00501 Peptidase_C15, 1 hit
Gene3Di3.40.630.20, 1 hit
HAMAPiMF_00417 Pyrrolid_peptidase, 1 hit
InterProiView protein in InterPro
IPR000816 Peptidase_C15
IPR016125 Peptidase_C15-like
IPR036440 Peptidase_C15-like_sf
IPR029762 PGP-I_bact-type
IPR033694 PGPEP1_Cys_AS
IPR033693 PGPEP1_Glu_AS
PANTHERiPTHR23402 PTHR23402, 1 hit
PfamiView protein in Pfam
PF01470 Peptidase_C15, 1 hit
PIRSFiPIRSF015592 Prld-crbxl_pptds, 1 hit
PRINTSiPR00706 PYROGLUPTASE
SUPFAMiSSF53182 SSF53182, 1 hit
TIGRFAMsiTIGR00504 pyro_pdase, 1 hit
PROSITEiView protein in PROSITE
PS01334 PYRASE_CYS, 1 hit
PS01333 PYRASE_GLU, 1 hit

Sequencei

Sequence statusi: Complete.

B7JDC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTVLLTGFD PFGGESINPA WEVAKSLHEK TIGEYKIISK QVPTVFHKSI
60 70 80 90 100
SVLKEYIEEL APECIICIGQ AGGRPDITIE RVAINIDDAR IADNEGNQPV
110 120 130 140 150
DVPVVEEGPA AYWSTLPMKA IVKKLQEEGI PASVSQTAGT FVCNHLFYGL
160 170 180 190 200
MHELEKHDTK MKGGFIHIPF LPEQASNYPG QPSMSLSTIR KGIELAVEVT
210
TTVEVDIVEI GGATH
Length:215
Mass (Da):23,453
Last modified:February 10, 2009 - v1
Checksum:iB2040BEEE870D7F0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001283 Genomic DNA Translation: ACK87438.1
RefSeqiWP_000859730.1, NC_011773.1

Genome annotation databases

EnsemblBacteriaiACK87438; ACK87438; BCAH820_3096
KEGGibcu:BCAH820_3096

Similar proteinsi

Entry informationi

Entry nameiPCP_BACC0
AccessioniPrimary (citable) accession number: B7JDC3
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: May 23, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Peptidase families
    Classification of peptidase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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