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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455) (Ferrobacillus ferrooxidans (strain ATCC 23270))
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei146UniRule annotation1
Active sitei586UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
Ordered Locus Names:AFE_1883Imported
OrganismiAcidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455) (Ferrobacillus ferrooxidans (strain ATCC 23270))Imported
Taxonomic identifieri243159 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAcidithiobacilliaAcidithiobacillalesAcidithiobacillaceaeAcidithiobacillus
Proteomesi
  • UP000001362 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PaxDbiB7JBY5

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi243159.AFE_1883

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT
OrthoDBiPOG091H040O

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

B7JBY5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKKALNGKA LRNRVKLLGN LLGEVLREQA GHRVFNAVEQ LRQGYIRLHK
60 70 80 90 100
REDLRLRERL ARFIDALPQD DLVLVIRAFN TYFSLVNIAE EEFQHLHRRR
110 120 130 140 150
LLQKGSMLWT GSFEETFREL QGQGINPGQL QFLLDQIRYL PVFTAHPTES
160 170 180 190 200
KRRTVLHALR RIFVTSKMLD DSALNDEEEQ EVMDNLRAQI QILWETEEVR
210 220 230 240 250
TNKPQVQDEV ENGLFYFRDS LFEAVPLTYR AARRAARRVF ANADIDIPAF
260 270 280 290 300
IRFGSWIGGD RDGNPNVTAA ITGWALRTQS IEVLKEYQQR LSDLYQLLGH
310 320 330 340 350
SSRFCAISPV LLASLERDAD DFPELAEWVD QRFPSEPYRR KLRYMMTRLD
360 370 380 390 400
LRLRQLENGQ VLNESAGPAY AAAEDFLDDL LLVRDSLRGH NDGYIADNEV
410 420 430 440 450
QEIIWLVQTF GFHLANLDIR QESSVHSRTI AELFAGIPGF ANYVELSEEA
460 470 480 490 500
RMLALSDALR RPGPLVEQAP DLSPMAAETC AMFRCIAQLR REVSTAGFGN
510 520 530 540 550
YVISMTHEAS HIMEVLVLAK EFGLAGWSRQ GLYSEIAVTP LFETIHDLER
560 570 580 590 600
MDTVMSTLLD NPVYAKILGS QDDIQEVMLG YSDSCKDGGI LSSSWSLYQA
610 620 630 640 650
QLRLAALADK RKIRIRVFHG RGGSVGRGGG PTYEAILAQP PDTVRGQIKI
660 670 680 690 700
TEQGEVLSFK YANLETAVYE LTVGTAGLIK ASIGLVRSAS GDNPDHLKIM
710 720 730 740 750
AELTRTGEAV YRDLTEGTPG FMDYFYEATP LNEIAHMNIG SRPSHRQRGD
760 770 780 790 800
RSMSSIRAIP WIFAWAQSRH VLPAWYGLGS ALARWREDKP ERLQALQDMY
810 820 830 840 850
RHWPFFRALM GNIGMAMAKT DMAIAGEYAG LPNDRDAAIA IYRKIQAEFE
860 870 880 890 900
SSQAEMLAIV GADHLLADNP TLAFSLQRRN VYMEPLNHIQ LALLRRYRND
910 920
ETPPEFREIW LDPLLRTINA ISAGQRNTG
Length:929
Mass (Da):105,418
Last modified:February 10, 2009 - v1
Checksum:iF8443F969083CBD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001219 Genomic DNA Translation: ACK80073.1
RefSeqiWP_012536819.1, NC_011761.1

Genome annotation databases

EnsemblBacteriaiACK80073; ACK80073; AFE_1883
KEGGiafr:AFE_1883

Similar proteinsi

Entry informationi

Entry nameiB7JBY5_ACIF2
AccessioniPrimary (citable) accession number: B7JBY5
Entry historyiIntegrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: March 28, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health