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B7J7X4

- DCD_ACIF2

UniProt

B7J7X4 - DCD_ACIF2

Protein

Deoxycytidine triphosphate deaminase

Gene

dcd

Organism
Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / NCIB 8455) (Ferrobacillus ferrooxidans (strain ATCC 23270))
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (10 Feb 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    dCTP + H2O = dUTP + NH3.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. dCTP deaminase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. dUMP biosynthetic process Source: UniProtKB-UniPathway
    2. dUTP biosynthetic process Source: InterPro
    3. pyrimidine ribonucleotide biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    Nucleotide metabolism

    Enzyme and pathway databases

    BioCyciAFER243159:GH3S-2655-MONOMER.
    UniPathwayiUPA00610; UER00665.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Deoxycytidine triphosphate deaminaseUniRule annotation (EC:3.5.4.13UniRule annotation)
    Short name:
    dCTP deaminaseUniRule annotation
    Gene namesi
    Name:dcdUniRule annotation
    Ordered Locus Names:AFE_2660
    OrganismiAcidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / NCIB 8455) (Ferrobacillus ferrooxidans (strain ATCC 23270))
    Taxonomic identifieri243159 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAcidithiobacillalesAcidithiobacillaceaeAcidithiobacillus
    ProteomesiUP000001362: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 188188Deoxycytidine triphosphate deaminasePRO_1000189820Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi243159.AFE_2660.

    Structurei

    3D structure databases

    ProteinModelPortaliB7J7X4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the dCTP deaminase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0717.
    HOGENOMiHOG000228600.
    KOiK01494.
    OMAiFFEGEPC.
    OrthoDBiEOG67DPKR.

    Family and domain databases

    Gene3Di2.70.40.10. 1 hit.
    HAMAPiMF_00146. dCTP_deaminase.
    InterProiIPR011962. dCTP_deam.
    IPR029054. dUTPase-like.
    IPR008180. dUTPase/dCTP_deaminase.
    [Graphical view]
    PfamiPF00692. dUTPase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51283. SSF51283. 1 hit.
    TIGRFAMsiTIGR02274. dCTP_deam. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    B7J7X4-1 [UniParc]FASTAAdd to Basket

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    MSIKSDRWIR HMAEEHGMIE PFSPRQVRHV EGNSIISYGL SSYGYDIRCA    50
    GEFKVFTNVR SVIVDPKNFS EHSFVDFTGD TCIIPPNSFA LARTLEYFRI 100
    PRNVLTICLG KSTYARCGII VNVTPFEPEW EGYVTLEFSN TTPLPAKIYA 150
    NEGVAQVLFL ESDEVCEVSY ADRGGKYQGQ SGVTLPKA 188
    Length:188
    Mass (Da):21,104
    Last modified:February 10, 2009 - v1
    Checksum:iFE83FC59E602F553
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001219 Genomic DNA. Translation: ACK80821.1.
    RefSeqiYP_002427037.1. NC_011761.1.

    Genome annotation databases

    EnsemblBacteriaiACK80821; ACK80821; AFE_2660.
    GeneIDi7134128.
    KEGGiafr:AFE_2660.
    PATRICi20656327. VBIAciFer29821_2417.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001219 Genomic DNA. Translation: ACK80821.1 .
    RefSeqi YP_002427037.1. NC_011761.1.

    3D structure databases

    ProteinModelPortali B7J7X4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243159.AFE_2660.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACK80821 ; ACK80821 ; AFE_2660 .
    GeneIDi 7134128.
    KEGGi afr:AFE_2660.
    PATRICi 20656327. VBIAciFer29821_2417.

    Phylogenomic databases

    eggNOGi COG0717.
    HOGENOMi HOG000228600.
    KOi K01494.
    OMAi FFEGEPC.
    OrthoDBi EOG67DPKR.

    Enzyme and pathway databases

    UniPathwayi UPA00610 ; UER00665 .
    BioCyci AFER243159:GH3S-2655-MONOMER.

    Family and domain databases

    Gene3Di 2.70.40.10. 1 hit.
    HAMAPi MF_00146. dCTP_deaminase.
    InterProi IPR011962. dCTP_deam.
    IPR029054. dUTPase-like.
    IPR008180. dUTPase/dCTP_deaminase.
    [Graphical view ]
    Pfami PF00692. dUTPase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51283. SSF51283. 1 hit.
    TIGRFAMsi TIGR02274. dCTP_deam. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Acidithiobacillus ferrooxidans metabolism: from genome sequence to industrial applications."
      Valdes J., Pedroso I., Quatrini R., Dodson R.J., Tettelin H., Blake R. II, Eisen J.A., Holmes D.S.
      BMC Genomics 9:597-597(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 23270 / DSM 14882 / NCIB 8455.

    Entry informationi

    Entry nameiDCD_ACIF2
    AccessioniPrimary (citable) accession number: B7J7X4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 14, 2009
    Last sequence update: February 10, 2009
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3