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B7J787 (B7J787_ACIF2) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 38. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length243 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP) By similarity. HAMAP-Rule MF_01200 SAAS SAAS018089

Catalytic activity

Orotidine 5'-phosphate = UMP + CO2. HAMAP-Rule MF_01200

Pathway

Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2. HAMAP-Rule MF_01200

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_01200 SAAS SAAS018089

Sequence similarities

Belongs to the OMP decarboxylase family. Type 1 subfamily. HAMAP-Rule MF_01200

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region62 – 7110Substrate binding By similarity HAMAP-Rule MF_01200

Sites

Active site641Proton donor By similarity HAMAP-Rule MF_01200
Binding site131Substrate By similarity HAMAP-Rule MF_01200
Binding site351Substrate By similarity HAMAP-Rule MF_01200
Binding site1231Substrate By similarity HAMAP-Rule MF_01200
Binding site1831Substrate By similarity HAMAP-Rule MF_01200
Binding site1921Substrate By similarity HAMAP-Rule MF_01200
Binding site2121Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01200
Binding site2131Substrate By similarity HAMAP-Rule MF_01200

Sequences

Sequence LengthMass (Da)Tools
B7J787 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: BB2D9C715522F9AC

FASTA24325,808
        10         20         30         40         50         60 
MQLVISPLII ALDYADERDA LILADQLDPA QCRVKVGKEL FTASGPSIVE RLQERGFDVF 

        70         80         90        100        110        120 
LDLKFHDIPQ TVAKACRAAS RLGVWMLNVH ASGGSAMLRA AREAVEDGGG TRRPLLIAVT 

       130        140        150        160        170        180 
VLTSMDDDAL HEVGVNSSVV EQVGRLATLA AACALDGLVC SALEADRLRN VLPELLRVTP 

       190        200        210        220        230        240 
GIRPAQYAED DQRRIMTPAA ALAAGSDFLV VGRPVTAAVD PARALGQILN ELVAKPGDSR 


EPG 

« Hide

References

[1]"Acidithiobacillus ferrooxidans metabolism: from genome sequence to industrial applications."
Valdes J., Pedroso I., Quatrini R., Dodson R.J., Tettelin H., Blake R.II., Eisen J.A., Holmes D.S.
BMC Genomics 9:597-597(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 23270 / DSM 14882 / NCIB 8455.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001219 Genomic DNA. Translation: ACK78323.1.
RefSeqYP_002425385.1. NC_011761.1.

3D structure databases

ProteinModelPortalB7J787.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243159.AFE_0907.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACK78323; ACK78323; AFE_0907.
GeneID7136586.
KEGGafr:AFE_0907.
PATRIC20653123. VBIAciFer29821_0869.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0284.
HOGENOMHOG000226070.
KOK01591.
OMANFKIFLD.
OrthoDBEOG6N6815.
ProtClustDBCLSK2407750.

Enzyme and pathway databases

BioCycAFER243159:GH3S-907-MONOMER.
UniPathwayUPA00070; UER00120.

Family and domain databases

Gene3D3.20.20.70. 1 hit.
HAMAPMF_01200_B. OMPdecase_type1_B.
InterProIPR013785. Aldolase_TIM.
IPR014732. OMPdecase.
IPR018089. OMPdecase_AS.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMSSF51366. SSF51366. 1 hit.
TIGRFAMsTIGR01740. pyrF. 1 hit.
PROSITEPS00156. OMPDECASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB7J787_ACIF2
AccessionPrimary (citable) accession number: B7J787
Entry history
Integrated into UniProtKB/TrEMBL: February 10, 2009
Last sequence update: February 10, 2009
Last modified: April 16, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)