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B7J4T0

- TRPF_ACIF2

UniProt

B7J4T0 - TRPF_ACIF2

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / NCIB 8455) (Ferrobacillus ferrooxidans (strain ATCC 23270))
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciAFER243159:GH3S-2065-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation (EC:5.3.1.24UniRule annotation)
Short name:
PRAIUniRule annotation
Gene namesi
Name:trpFUniRule annotation
Ordered Locus Names:AFE_2070
OrganismiAcidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / NCIB 8455) (Ferrobacillus ferrooxidans (strain ATCC 23270))
Taxonomic identifieri243159 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAcidithiobacillalesAcidithiobacillaceaeAcidithiobacillus
ProteomesiUP000001362: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 205205N-(5'-phosphoribosyl)anthranilate isomerasePRO_1000197070Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243159.AFE_2070.

Structurei

3D structure databases

ProteinModelPortaliB7J4T0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiADCEGYH.
OrthoDBiEOG6N94DF.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

B7J4T0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPMVRIKICG ITNTEDARAA AAAGADAVGL VFYRSSPRAL DAVRARKILA
60 70 80 90 100
ALPPFVTRVG LFVNAEAADV AATLQQCPLD VLQFHGDESP SLCRGFGRPY
110 120 130 140 150
IKVLRVTAAQ DLRPAVDAYH DAQGLLLDCA APGVWGGSGR SFDWWRLPDL
160 170 180 190 200
GKPLILAGGL HAENVAEAIA IARPYAVDVS SGVELSPGRK DHDKMARFVA

RVRGT
Length:205
Mass (Da):21,827
Last modified:February 10, 2009 - v1
Checksum:iAACF86804C68B24D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001219 Genomic DNA. Translation: ACK78247.1.
RefSeqiWP_012607306.1. NC_011761.1.
YP_002426473.1. NC_011761.1.

Genome annotation databases

EnsemblBacteriaiACK78247; ACK78247; AFE_2070.
GeneIDi7134282.
KEGGiafr:AFE_2070.
PATRICi20655251. VBIAciFer29821_1890.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001219 Genomic DNA. Translation: ACK78247.1 .
RefSeqi WP_012607306.1. NC_011761.1.
YP_002426473.1. NC_011761.1.

3D structure databases

ProteinModelPortali B7J4T0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243159.AFE_2070.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACK78247 ; ACK78247 ; AFE_2070 .
GeneIDi 7134282.
KEGGi afr:AFE_2070.
PATRICi 20655251. VBIAciFer29821_1890.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi ADCEGYH.
OrthoDBi EOG6N94DF.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci AFER243159:GH3S-2065-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Acidithiobacillus ferrooxidans metabolism: from genome sequence to industrial applications."
    Valdes J., Pedroso I., Quatrini R., Dodson R.J., Tettelin H., Blake R. II, Eisen J.A., Holmes D.S.
    BMC Genomics 9:597-597(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 23270 / DSM 14882 / NCIB 8455.

Entry informationi

Entry nameiTRPF_ACIF2
AccessioniPrimary (citable) accession number: B7J4T0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: November 26, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3