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Protein

60 kDa chaperonin

Gene

groL

Organism
Borrelia burgdorferi (strain ZS7)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation, mopA
Ordered Locus Names:BbuZS7_0669
OrganismiBorrelia burgdorferi (strain ZS7)
Taxonomic identifieri445985 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorreliella
Proteomesi
  • UP000006901 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001299781 – 54560 kDa chaperoninAdd BLAST545

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB7J2K5.
SMRiB7J2K5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000076290.
KOiK04077.
OMAiTDTDKME.

Family and domain databases

CDDicd03344. GroEL. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.50.7.10. 1 hit.
HAMAPiMF_00600. CH60. 1 hit.
InterProiView protein in InterPro
IPR018370. Chaperonin_Cpn60_CS.
IPR001844. Chaprnin_Cpn60.
IPR002423. Cpn60/TCP-1.
IPR037290. Cpn60/TCP-1_sf.
IPR027409. GroEL-like_apical_dom_sf.
IPR027413. GROEL-like_equatorial_sf.
PANTHERiPTHR11353. PTHR11353. 1 hit.
PfamiView protein in Pfam
PF00118. Cpn60_TCP1. 1 hit.
PRINTSiPR00298. CHAPERONIN60.
SUPFAMiSSF48592. SSF48592. 2 hits.
SSF52029. SSF52029. 1 hit.
SSF54849. SSF54849. 1 hit.
TIGRFAMsiTIGR02348. GroEL. 1 hit.
PROSITEiView protein in PROSITE
PS00296. CHAPERONINS_CPN60. 1 hit.

Sequencei

Sequence statusi: Complete.

B7J2K5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKDIYFNED ARKSLLSGVE KLSNAVKVTL GPKGRNVLID KKFGSPTVTK
60 70 80 90 100
DGVSVAREIE LENPFENMGA QLLKEVAIKT NDVAGDGTTT ATVLAYAIAR
110 120 130 140 150
EGLKNVSSGI NPIGIKKGID HAVNLAAEKI RQSAKKITTK EEIAQVASIS
160 170 180 190 200
ANNDSYIGEK IAEAMDKVGK DGVITVEESK TFDTTISYVE GMQFDRGYLS
210 220 230 240 250
PYFSTNKENM SVNFDDAFIL IYEKKISSIK ELLPVLEKVL GTNKPLLIIA
260 270 280 290 300
EDIEGDALAA LVLNSVRGAL KVCAIKSPGF GDRRKAMLED IAVLTGGVLI
310 320 330 340 350
SEELGLTLET VEIEQLGQAK TIKVDKDNTT IINTGNKEQI KERSELIKKQ
360 370 380 390 400
IEDSTSEYDK EKLQERLAKL VGGVAVINVG AVTEVELKEK KHRVEDALSA
410 420 430 440 450
TRAAVEEGVV PGGGSTLIEV AMYLDTIDTS KLSYEEKQGF EIVKRSLEEP
460 470 480 490 500
MRQIISNAGF EGSIYIHQIK TEKKGLGFDA SSFKWVNMIE SGIIDPAKVT
510 520 530 540
RSALQNAASI AGLLLTTECA ITDIKEEKNT SGGGGYPMDP GMGMM
Length:545
Mass (Da):58,952
Last modified:February 10, 2009 - v1
Checksum:i568BA8E5B4835719
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X65139 Genomic DNA. Translation: CAA46269.1.
CP001205 Genomic DNA. Translation: ACK75110.1.
PIRiH70180.
RefSeqiWP_002657108.1. NC_011728.1.

Genome annotation databases

EnsemblBacteriaiACK75110; ACK75110; BbuZS7_0669.
KEGGibbz:BbuZS7_0669.

Similar proteinsi

Entry informationi

Entry nameiCH60_BORBZ
AccessioniPrimary (citable) accession number: B7J2K5
Secondary accession number(s): P27575
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: November 22, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families