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B7J2I0 (ACKA_BORBZ) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:BbuZS7_0641
OrganismBorrelia burgdorferi (strain ZS7) [Complete proteome] [HAMAP]
Taxonomic identifier445985 [NCBI]
Taxonomic lineageBacteria › Spirochaetes › Spirochaetales › Spirochaetaceae › Borrelia › Borrelia burgdorferi group

Protein attributes

Sequence length405 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 405405Acetate kinase HAMAP MF_00020
PRO_1000116386

Sequences

Sequence LengthMass (Da)Tools
B7J2I0 [UniParc].

Last modified February 10, 2009. Version 1.
Checksum: 0EB43AAA765AFE37

FASTA40545,336
        10         20         30         40         50         60 
MKILIINTGS SSLKFAIYQY ENSKKIISGI VEKIKSQKSI IKIVNTDGST TERFEKGIEN 

        70         80         90        100        110        120 
HQKAIEKMFK ILTNSDLKIL KTLSEIKIIG HRVVHGGSSL KNSVILNNSI LNKLKQISEL 

       130        140        150        160        170        180 
APLHNPNAIT AIEAVLKILP HAKQVLCFDT SWHQTIKEHA FLYAIPYSWY KNHNIRKYGF 

       190        200        210        220        230        240 
HGLSYSYITK RSSEILNKKI DSLNLIILHL GNGASINAVK NGKSYDTSMG ITPLEGLAMG 

       250        260        270        280        290        300 
TRSGDIDPSI INLMSTILNK TTKQIEEILN KESGILGISE KSNDMRDIWN KIEEGEYQSK 

       310        320        330        340        350        360 
LAVEIMTYRI KKYIGSYIAA LDFNVDAIVF TGGIGVTDYG IRALALKGFE KIGIELDLEK 

       370        380        390        400 
NEMAQSKYLE SEISTINSKL KILAIPTNEE STILEDIYNL IPKNL

« Hide

References

[1]"Whole-genome sequences of thirteen isolates of Borrelia burgdorferi."
Schutzer S.E., Fraser-Liggett C.M., Casjens S.R., Qiu W.G., Dunn J.J., Mongodin E.F., Luft B.J.
J. Bacteriol. 193:1018-1020(2011) [PubMed: 20935092] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ZS7.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001205 Genomic DNA. Translation: ACK74517.1.
RefSeqYP_002375125.1. NC_011728.1.

3D structure databases

ProteinModelPortalB7J2I0.
ModBaseSearch...

Protein-protein interaction databases

STRINGB7J2I0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBORT00000003240; EBBORP00000002979; EBBORG00000003240.
GeneID7106719.
GenomeReviewsGene locus BbuZS7_0641 in contig CP001205_GR.
KEGGbbz:BbuZS7_0641.
PATRIC20560711. VBIBorBur54821_0754.

Organism-specific databases

CMRSearch...

Phylogenomic databases

GeneTreeEBGT00050000007562.
HOGENOMHBG285863.
OMAERNNIRA.
ProtClustDBPRK00180.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_BORBZ
AccessionPrimary (citable) accession number: B7J2I0
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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