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Protein

UvrABC system protein C

Gene

uvrC

Organism
Borrelia burgdorferi (strain ZS7)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionExcision nuclease
Biological processDNA damage, DNA excision, DNA repair, SOS response

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein CUniRule annotation
Short name:
Protein UvrCUniRule annotation
Alternative name(s):
Excinuclease ABC subunit CUniRule annotation
Gene namesi
Name:uvrCUniRule annotation
Ordered Locus Names:BbuZS7_0464
OrganismiBorrelia burgdorferi (strain ZS7)
Taxonomic identifieri445985 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorreliella
Proteomesi
  • UP000006901 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10002005731 – 603UvrABC system protein CAdd BLAST603

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliB7J223
SMRiB7J223
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini17 – 94GIY-YIGUniRule annotationAdd BLAST78

Sequence similaritiesi

Belongs to the UvrC family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000279960
KOiK03703
OMAiLFPIRQC

Family and domain databases

Gene3Di3.30.420.340, 1 hit
3.40.1440.10, 1 hit
HAMAPiMF_00203 UvrC, 1 hit
InterProiView protein in InterPro
IPR000305 GIY-YIG_endonuc
IPR035901 GIY-YIG_endonuc_sf
IPR010994 RuvA_2-like
IPR004791 UvrC
IPR001162 UvrC_homol_region
IPR038476 UvrC_homol_region_sf
PfamiView protein in Pfam
PF01541 GIY-YIG, 1 hit
PF08459 UvrC_HhH_N, 1 hit
SMARTiView protein in SMART
SM00465 GIYc, 1 hit
SUPFAMiSSF47781 SSF47781, 1 hit
SSF82771 SSF82771, 1 hit
TIGRFAMsiTIGR00194 uvrC, 1 hit
PROSITEiView protein in PROSITE
PS50164 GIY_YIG, 1 hit
PS50165 UVRC, 1 hit

Sequencei

Sequence statusi: Complete.

B7J223-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKENLTNLFE KVIKLPTTSG CYKMLNENKK ILYIGKAKNL RSRVKSYFLE
60 70 80 90 100
KNSHKIKILM KNVKSIEVIT TNSEYEALLL ECNLIKTHKP DYNVKLKDGK
110 120 130 140 150
GYPMVRITHE KYPRIFKTRK IINDKSEYFG PFTNVKKLDQ VLDFINKTFK
160 170 180 190 200
IRKCKKKSNA PCLYYHMGQC LGVCYKENLE KEYQKELDKA KSILNGNISE
210 220 230 240 250
ISSQIDIKLK HAIQKEDFET AIKLKEIRNS LIEINQIQIV TKTNNLNIDY
260 270 280 290 300
VHVHPGENVN TIIVLKYRNG KLVERDANFD ESICKENELI LQFLIQYYTS
310 320 330 340 350
INMIVPDKIH IFLKDIDTKN VEKLINEIKN TKTEIIYKET EEILKIMEMA
360 370 380 390 400
ISNAELSLRE YENKSTKALE SLKIVLEMDK LPKIIEGFDI AHLKGQETVA
410 420 430 440 450
SMVTFKMGMP FKENYRLYKL NSLLKGEIDD FKAIKEVISR RYSEIINNNL
460 470 480 490 500
ELPNLILIDG GKGQLNAALS ILKGLKIENK VKVCSLAKKQ ETIFLTTNKK
510 520 530 540 550
GINLPQGHPA LRILQNVRDE AHRKANGFNK KRREKITLLY TKIHGIGEKT
560 570 580 590 600
AQKILKSIGT YKDILPLSEN EISEKIKVNV QLAKRIKEFA IKENSIKNNN

QDK
Length:603
Mass (Da):69,833
Last modified:February 10, 2009 - v1
Checksum:iB9EDDDB6B4A63484
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001205 Genomic DNA Translation: ACK74967.1
RefSeqiWP_002657940.1, NC_011728.1

Genome annotation databases

EnsemblBacteriaiACK74967; ACK74967; BbuZS7_0464
KEGGibbz:BbuZS7_0464

Similar proteinsi

Entry informationi

Entry nameiUVRC_BORBZ
AccessioniPrimary (citable) accession number: B7J223
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: February 10, 2009
Last modified: May 23, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

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